BRD-K96147838_5-bromo-2-(4-(tert-butyl)benzamido)-4-chlorobenzoic acid KUC107591N_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K96147838_5-bromo-2-(4-(tert-butyl)benzamido)-4-chlorobenzoic acid KUC107591N_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADAMDEC1 ADAM-like, decysin 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ATP11B ATPase, class VI, type 11B
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CCL19 chemokine (C-C motif) ligand 19
CCL5 chemokine (C-C motif) ligand 5
CD2 CD2 molecule
CD8A CD8a molecule
CDK19 cyclin-dependent kinase 19
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
COL3A1 collagen, type III, alpha 1
CST7 cystatin F (leukocystatin)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
DSTN destrin (actin depolymerizing factor)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM129A family with sequence similarity 129, member A
GBP1 guanylate binding protein 1, interferon-inducible
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KLK5 kallikrein-related peptidase 5
KLK6 kallikrein-related peptidase 6
LAMP3 lysosomal-associated membrane protein 3
LDB3 LIM domain binding 3
LOC100505650 uncharacterized LOC100505650
LTF lactotransferrin
LUM lumican
MAOB monoamine oxidase B
NEB nebulin
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTN pleiotrophin
RNH1 ribonuclease/angiogenin inhibitor 1
S100A8 S100 calcium binding protein A8
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLPI secretory leukocyte peptidase inhibitor
SOX9 SRY (sex determining region Y)-box 9
SPARCL1 SPARC-like 1 (hevin)
SRGN serglycin
TGM4 transglutaminase 4
TM4SF1 transmembrane 4 L six family member 1
TMOD1 tropomodulin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BACE2 beta-site APP-cleaving enzyme 2
BID BH3 interacting domain death agonist
CCND2 cyclin D2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLDN1 claudin 1
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DHRS2 dehydrogenase/reductase (SDR family) member 2
ELF1 E74-like factor 1 (ets domain transcription factor)
GOLT1B golgi transport 1B
GPX7 glutathione peroxidase 7
GSTM3 glutathione S-transferase mu 3 (brain)
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
MFAP5 microfibrillar associated protein 5
MMD monocyte to macrophage differentiation-associated
NBPF10 neuroblastoma breakpoint family, member 10
NUP93 nucleoporin 93kDa
PTX3 pentraxin 3, long
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RPIA ribose 5-phosphate isomerase A
SGCE sarcoglycan, epsilon
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SRRM2 serine/arginine repetitive matrix 2
STC1 stanniocalcin 1
SYBU syntabulin (syntaxin-interacting)
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI2 tissue factor pathway inhibitor 2
TMF1 TATA element modulatory factor 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZC3H13 zinc finger CCCH-type containing 13