BRD-K95760042_2512-0754_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

24 genes differentially expressed following the BRD-K95760042_2512-0754_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
CD14 CD14 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CLU clusterin
GJA1 gap junction protein, alpha 1, 43kDa
GSTA4 glutathione S-transferase alpha 4
IGKC immunoglobulin kappa constant
KLF4 Kruppel-like factor 4 (gut)
NID2 nidogen 2 (osteonidogen)
NT5DC2 5'-nucleotidase domain containing 2
PRF1 perforin 1 (pore forming protein)
SCGB2A2 secretoglobin, family 2A, member 2
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADGRG2 adhesion G protein-coupled receptor G2
ALDOB aldolase B, fructose-bisphosphate
CD52 CD52 molecule
DACH1 dachshund family transcription factor 1
HSPA1A heat shock 70kDa protein 1A
IGF1R insulin-like growth factor 1 receptor
LYPD1 LY6/PLAUR domain containing 1
MSLN mesothelin
RAB13 RAB13, member RAS oncogene family