BRD-K94841585_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

90 genes differentially expressed following the BRD-K94841585_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTC1 actin, alpha, cardiac muscle 1
ADGRA2 adhesion G protein-coupled receptor A2
CCL5 chemokine (C-C motif) ligand 5
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD200 CD200 molecule
CD36 CD36 molecule (thrombospondin receptor)
CECR1 cat eye syndrome chromosome region, candidate 1
CES1 carboxylesterase 1
COL1A1 collagen, type I, alpha 1
COL9A2 collagen, type IX, alpha 2
CPE carboxypeptidase E
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EIF5A eukaryotic translation initiation factor 5A
FAM129A family with sequence similarity 129, member A
FGFR2 fibroblast growth factor receptor 2
IGFBP5 insulin-like growth factor binding protein 5
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MEF2C myocyte enhancer factor 2C
MEIS2 Meis homeobox 2
NEB nebulin
NPTX2 neuronal pentraxin II
PECAM1 platelet/endothelial cell adhesion molecule 1
PLVAP plasmalemma vesicle associated protein
POSTN periostin, osteoblast specific factor
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SH3BGRL SH3 domain binding glutamate-rich protein like
SHB Src homology 2 domain containing adaptor protein B
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
TPM1 tropomyosin 1 (alpha)
TWIST1 twist family bHLH transcription factor 1

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADD3 adducin 3 (gamma)
ADGRG6 adhesion G protein-coupled receptor G6
ADIRF adipogenesis regulatory factor
AQP3 aquaporin 3 (Gill blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
C8ORF4 chromosome 8 open reading frame 4
CALD1 caldesmon 1
CAST calpastatin
CCND2 cyclin D2
CD59 CD59 molecule, complement regulatory protein
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLIC4 chloride intracellular channel 4
CLU clusterin
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CXADR coxsackie virus and adenovirus receptor
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DST dystonin
F3 coagulation factor III (thromboplastin, tissue factor)
FGFR3 fibroblast growth factor receptor 3
GMDS GDP-mannose 4,6-dehydratase
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGKV4-1 immunoglobulin kappa variable 4-1
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LXN latexin
MAP7 microtubule-associated protein 7
METTL7A methyltransferase like 7A
MT1X metallothionein 1X
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIB nuclear factor I/B
PCSK1 proprotein convertase subtilisin/kexin type 1
PON2 paraoxonase 2
POU2AF1 POU class 2 associating factor 1
PRKD3 protein kinase D3
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SASH1 SAM and SH3 domain containing 1
SEPP1 selenoprotein P, plasma, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SIK1 salt-inducible kinase 1
TACSTD2 tumor-associated calcium signal transducer 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TJP2 tight junction protein 2
TM4SF1 transmembrane 4 L six family member 1
TSC22D1 TSC22 domain family, member 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF586 zinc finger protein 586