BRD-K94176593_TWS-119_PC3_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

78 genes differentially expressed following the BRD-K94176593_TWS-119_PC3_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA12 carbonic anhydrase XII
CCNB2 cyclin B2
CFD complement factor D (adipsin)
CKB creatine kinase, brain
CPB1 carboxypeptidase B1 (tissue)
CXCL9 chemokine (C-X-C motif) ligand 9
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
ELANE elastase, neutrophil expressed
FN1 fibronectin 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GATA6 GATA binding protein 6
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
IDO1 indoleamine 2,3-dioxygenase 1
KLK10 kallikrein-related peptidase 10
KRT18 keratin 18, type I
LGALS2 lectin, galactoside-binding, soluble, 2
LYZ lysozyme
MSLN mesothelin
MUC4 mucin 4, cell surface associated
MYO5C myosin VC
NUPR1 nuclear protein, transcriptional regulator, 1
PRTN3 proteinase 3
RBM47 RNA binding motif protein 47
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADIRF adipogenesis regulatory factor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C6ORF62 chromosome 6 open reading frame 62
CD59 CD59 molecule, complement regulatory protein
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
EGFR epidermal growth factor receptor
FHL1 four and a half LIM domains 1
GOLT1B golgi transport 1B
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
INHBA inhibin, beta A
KRT7 keratin 7, type II
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
MMP3 matrix metallopeptidase 3
NEBL nebulette
NR1D2 nuclear receptor subfamily 1, group D, member 2
POSTN periostin, osteoblast specific factor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RECQL RecQ helicase-like
SDC2 syndecan 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGCE sarcoglycan, epsilon
SPP1 secreted phosphoprotein 1
SSBP2 single-stranded DNA binding protein 2
STOM stomatin
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM47 transmembrane protein 47
TNC tenascin C
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
WNT5A wingless-type MMTV integration site family, member 5A
ZIC1 Zic family member 1