BRD-K94176593_TWS-119_HS578T_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-K94176593_TWS-119_HS578T_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABAT 4-aminobutyrate aminotransferase
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACKR3 atypical chemokine receptor 3
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRG2 adhesion G protein-coupled receptor G2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANGPTL2 angiopoietin-like 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASS1 argininosuccinate synthase 1
CDC14B cell division cycle 14B
CFB complement factor B
CLEC2B C-type lectin domain family 2, member B
COL15A1 collagen, type XV, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
EVI2A ecotropic viral integration site 2A
FAM46A family with sequence similarity 46, member A
FAM63A family with sequence similarity 63, member A
FOXO4 forkhead box O4
GAS1 growth arrest-specific 1
GNB5 guanine nucleotide binding protein (G protein), beta 5
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
ITM2A integral membrane protein 2A
LAPTM4B lysosomal protein transmembrane 4 beta
LITAF lipopolysaccharide-induced TNF factor
LY96 lymphocyte antigen 96
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MSRB1 methionine sulfoxide reductase B1
NR2F1 nuclear receptor subfamily 2, group F, member 1
OBSL1 obscurin-like 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZK1 PDZ domain containing 1
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSPH phosphoserine phosphatase
QKI QKI, KH domain containing, RNA binding
QPRT quinolinate phosphoribosyltransferase
RBP1 retinol binding protein 1, cellular
RCAN2 regulator of calcineurin 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL31 ribosomal protein L31
SCG2 secretogranin II
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SMAD3 SMAD family member 3
SPARCL1 SPARC-like 1 (hevin)
TCTN1 tectonic family member 1
TFF1 trefoil factor 1
TMEM45A transmembrane protein 45A
TNNT1 troponin T type 1 (skeletal, slow)
TOX3 TOX high mobility group box family member 3
TPP1 tripeptidyl peptidase I
TYRP1 tyrosinase-related protein 1
ZIC1 Zic family member 1

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AMIGO2 adhesion molecule with Ig-like domain 2
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CD24 CD24 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CES1 carboxylesterase 1
CTGF connective tissue growth factor
CTPS1 CTP synthase 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EDN1 endothelin 1
EYA2 EYA transcriptional coactivator and phosphatase 2
GADD45B growth arrest and DNA-damage-inducible, beta
GNAS GNAS complex locus
GSTP1 glutathione S-transferase pi 1
IER3 immediate early response 3
INHBA inhibin, beta A
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KRT18 keratin 18, type I
LTBP2 latent transforming growth factor beta binding protein 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MICALL1 MICAL-like 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NRIP1 nuclear receptor interacting protein 1
PDLIM5 PDZ and LIM domain 5
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SET SET nuclear proto-oncogene
SORBS2 sorbin and SH3 domain containing 2
SPP1 secreted phosphoprotein 1
STAT1 signal transducer and activator of transcription 1, 91kDa
SYNE2 spectrin repeat containing, nuclear envelope 2
TACSTD2 tumor-associated calcium signal transducer 2
ZW10 zw10 kinetochore protein