BRD-K94176593_TWS-119_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K94176593_TWS-119_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CFD complement factor D (adipsin)
CLDN10 claudin 10
DEFB1 defensin, beta 1
EPHA4 EPH receptor A4
FBLN1 fibulin 1
KLK6 kallikrein-related peptidase 6
LCN2 lipocalin 2
MAN1A1 mannosidase, alpha, class 1A, member 1
NEB nebulin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCQ protein kinase C, theta
RAB2A RAB2A, member RAS oncogene family
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100P S100 calcium binding protein P
STAB1 stabilin 1
VGLL1 vestigial-like family member 1

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
FOSL1 FOS-like antigen 1
GNAS GNAS complex locus
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL6 interleukin 6
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP12 matrix metallopeptidase 12
MYC v-myc avian myelocytomatosis viral oncogene homolog
POU2AF1 POU class 2 associating factor 1
PRKCA protein kinase C, alpha
REEP1 receptor accessory protein 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
VIM vimentin