BRD-K94176593_TWS-119_A375_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K94176593_TWS-119_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRL1 adhesion G protein-coupled receptor L1
AGR2 anterior gradient 2
ANXA4 annexin A4
ASS1 argininosuccinate synthase 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
AUTS2 autism susceptibility candidate 2
C1RL complement component 1, r subcomponent-like
CAPN1 calpain 1, (mu/I) large subunit
CD14 CD14 molecule
CD163 CD163 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES2 carboxylesterase 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRAT carnitine O-acetyltransferase
CST3 cystatin C
CX3CR1 chemokine (C-X3-C motif) receptor 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM63A family with sequence similarity 63, member A
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
GSN gelsolin
HIST1H2BK histone cluster 1, H2bk
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITFG1 integrin alpha FG-GAP repeat containing 1
KANK1 KN motif and ankyrin repeat domains 1
LIMCH1 LIM and calponin homology domains 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
METRN meteorin, glial cell differentiation regulator
MVP major vault protein
ORAI3 ORAI calcium release-activated calcium modulator 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH9 protocadherin 9
PLA2G16 phospholipase A2, group XVI
PON2 paraoxonase 2
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SLC22A18 solute carrier family 22, member 18
SOX2 SRY (sex determining region Y)-box 2
SPP1 secreted phosphoprotein 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TOX3 TOX high mobility group box family member 3
TPD52L1 tumor protein D52-like 1
TRIM22 tripartite motif containing 22
TYROBP TYRO protein tyrosine kinase binding protein
VAMP8 vesicle-associated membrane protein 8
VCAN versican

decreased expression

Symbol Name
ANXA3 annexin A3
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CAB39 calcium binding protein 39
CCL20 chemokine (C-C motif) ligand 20
CCNA2 cyclin A2
CCNB2 cyclin B2
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDCA4 cell division cycle associated 4
CENPN centromere protein N
CTGF connective tissue growth factor
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
GINS2 GINS complex subunit 2 (Psf2 homolog)
HMGB2 high mobility group box 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
INHBA inhibin, beta A
KIF14 kinesin family member 14
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCM5 minichromosome maintenance complex component 5
NRIP1 nuclear receptor interacting protein 1
PRC1 protein regulator of cytokinesis 1
RAD51AP1 RAD51 associated protein 1
RANBP1 RAN binding protein 1
RRM2 ribonucleotide reductase M2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SMS spermine synthase
STMN1 stathmin 1
TACSTD2 tumor-associated calcium signal transducer 2
TAGLN transgelin
TMPO thymopoietin
UGCG UDP-glucose ceramide glucosyltransferase
ZNF586 zinc finger protein 586