BRD-K93918653_quizartinib_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K93918653_quizartinib_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
AMDHD2 amidohydrolase domain containing 2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
BMP4 bone morphogenetic protein 4
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD9 CD9 molecule
COL11A1 collagen, type XI, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FAM69A family with sequence similarity 69, member A
GDF15 growth differentiation factor 15
GPX1 glutathione peroxidase 1
HOXB2 homeobox B2
HOXB6 homeobox B6
PIP prolactin-induced protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RND3 Rho family GTPase 3
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERINC5 serine incorporator 5
SFN stratifin
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQSTM1 sequestosome 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TPM2 tropomyosin 2 (beta)
TRAF5 TNF receptor-associated factor 5
TRIM22 tripartite motif containing 22
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
CCL20 chemokine (C-C motif) ligand 20
COX17 COX17 cytochrome c oxidase copper chaperone
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
FCGBP Fc fragment of IgG binding protein
GALC galactosylceramidase
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GPX3 glutathione peroxidase 3
ITM2A integral membrane protein 2A
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCKS myristoylated alanine-rich protein kinase C substrate
NBN nibrin
NUP62 nucleoporin 62kDa
PXMP2 peroxisomal membrane protein 2, 22kDa
RPS4Y1 ribosomal protein S4, Y-linked 1
SDC2 syndecan 2
SPON2 spondin 2, extracellular matrix protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TXNIP thioredoxin interacting protein