BRD-K93875449_5-amino-1-methyl-3-(naphthalen-1-ylmethyl)-1H-pyrazole-4-carbonitrile CAL-NCGC-039_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

41 genes differentially expressed following the BRD-K93875449_5-amino-1-methyl-3-(naphthalen-1-ylmethyl)-1H-pyrazole-4-carbonitrile CAL-NCGC-039_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AURKB aurora kinase B
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CD93 CD93 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CORO1A coronin, actin binding protein, 1A
CSRP2 cysteine and glycine-rich protein 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
FABP4 fatty acid binding protein 4, adipocyte
FAM107A family with sequence similarity 107, member A
FAM129A family with sequence similarity 129, member A
G0S2 G0/G1 switch 2
GSTT1 glutathione S-transferase theta 1
IGFBP7 insulin-like growth factor binding protein 7
KIAA0196 KIAA0196
LCN2 lipocalin 2
NPTX2 neuronal pentraxin II
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
PTPRK protein tyrosine phosphatase, receptor type, K
RGCC regulator of cell cycle
SGCE sarcoglycan, epsilon
SNX7 sorting nexin 7
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TSPAN12 tetraspanin 12
VWF von Willebrand factor

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
CA12 carbonic anhydrase XII
CKS2 CDC28 protein kinase regulatory subunit 2
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
GATA2 GATA binding protein 2
GCH1 GTP cyclohydrolase 1
GLRX glutaredoxin (thioltransferase)
HOXC6 homeobox C6
NCK2 NCK adaptor protein 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RPS27L ribosomal protein S27-like