BRD-K93788137_PF-431396_MCF10A_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K93788137_PF-431396_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACKR3 atypical chemokine receptor 3
AK4 adenylate kinase 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARG1 arginase 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CFB complement factor B
COMP cartilage oligomeric matrix protein
CRIP2 cysteine-rich protein 2
DLD dihydrolipoamide dehydrogenase
DSP desmoplakin
EGR1 early growth response 1
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
GCLC glutamate-cysteine ligase, catalytic subunit
GPX3 glutathione peroxidase 3
GSTM3 glutathione S-transferase mu 3 (brain)
GSTT1 glutathione S-transferase theta 1
HIST1H2BK histone cluster 1, H2bk
HIST1H4C histone cluster 1, H4c
HOXA5 homeobox A5
HP haptoglobin
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INHBA inhibin, beta A
JUP junction plakoglobin
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LYZ lysozyme
MMP9 matrix metallopeptidase 9
NCF2 neutrophil cytosolic factor 2
NMU neuromedin U
NSFL1C NSFL1 (p97) cofactor (p47)
PEG3 paternally expressed 3
RAB11FIP1 RAB11 family interacting protein 1 (class I)
REEP5 receptor accessory protein 5
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SESN1 sestrin 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
TBXA2R thromboxane A2 receptor
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM45A transmembrane protein 45A
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AQP3 aquaporin 3 (Gill blood group)
AXIN1 axin 1
CANT1 calcium activated nucleotidase 1
CCNF cyclin F
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
EIF5 eukaryotic translation initiation factor 5
FOXF2 forkhead box F2
FST follistatin
FZD7 frizzled class receptor 7
GRB10 growth factor receptor-bound protein 10
IFI44L interferon-induced protein 44-like
JADE2 jade family PHD finger 2
JCHAIN joining chain of multimeric IgA and IgM
KLHL9 kelch-like family member 9
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MCTP1 multiple C2 domains, transmembrane 1
MID1IP1 MID1 interacting protein 1
MYH11 myosin, heavy chain 11, smooth muscle
NRG1 neuregulin 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
TARBP1 TAR (HIV-1) RNA binding protein 1
TPM2 tropomyosin 2 (beta)
WLS wntless Wnt ligand secretion mediator
ZNF451 zinc finger protein 451