BRD-K93788137_PF-431396_HS578T_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K93788137_PF-431396_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ASPN asporin
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
CD38 CD38 molecule
CKB creatine kinase, brain
COL11A1 collagen, type XI, alpha 1
CPE carboxypeptidase E
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCLK1 doublecortin-like kinase 1
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUOX2 dual oxidase 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
FAM171A1 family with sequence similarity 171, member A1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GATA3 GATA binding protein 3
GPC4 glypican 4
GRB14 growth factor receptor-bound protein 14
GRIA2 glutamate receptor, ionotropic, AMPA 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LUM lumican
MAOB monoamine oxidase B
MATN2 matrilin 2
MT1F metallothionein 1F
NFIL3 nuclear factor, interleukin 3 regulated
NMU neuromedin U
PCP4 Purkinje cell protein 4
PLAC8 placenta-specific 8
PPARG peroxisome proliferator-activated receptor gamma
RRAGD Ras-related GTP binding D
SELENBP1 selenium binding protein 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SORD sorbitol dehydrogenase
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TMEM45A transmembrane protein 45A
TNC tenascin C
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ARID5B AT rich interactive domain 5B (MRF1-like)
C6ORF62 chromosome 6 open reading frame 62
CALML5 calmodulin-like 5
CXCL13 chemokine (C-X-C motif) ligand 13
EDN1 endothelin 1
EIF5 eukaryotic translation initiation factor 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOMER3 homer scaffolding protein 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
JMJD6 jumonji domain containing 6
KLF6 Kruppel-like factor 6
KRT14 keratin 14, type I
KRT18 keratin 18, type I
LMO4 LIM domain only 4
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MME membrane metallo-endopeptidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEK7 NIMA-related kinase 7
PLK2 polo-like kinase 2
PSRC1 proline/serine-rich coiled-coil 1
PTX3 pentraxin 3, long
RIN2 Ras and Rab interactor 2