BRD-K93788137_PF-431396_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K93788137_PF-431396_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARID5B AT rich interactive domain 5B (MRF1-like)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL20 chemokine (C-C motif) ligand 20
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFB complement factor B
CPT1A carnitine palmitoyltransferase 1A (liver)
CTTN cortactin
CX3CL1 chemokine (C-X3-C motif) ligand 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLK1 delta-like 1 homolog (Drosophila)
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FAM198B family with sequence similarity 198, member B
FBLN2 fibulin 2
FGB fibrinogen beta chain
FNBP1 formin binding protein 1
FXYD6 FXYD domain containing ion transport regulator 6
KRT23 keratin 23, type I
LDOC1 leucine zipper, down-regulated in cancer 1
MAP1B microtubule-associated protein 1B
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP7 matrix metallopeptidase 7
NCAM1 neural cell adhesion molecule 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PDZK1IP1 PDZK1 interacting protein 1
PLAT plasminogen activator, tissue
PROM1 prominin 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
SEPP1 selenoprotein P, plasma, 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STC1 stanniocalcin 1
SYBU syntabulin (syntaxin-interacting)
TWF2 twinfilin actin binding protein 2

decreased expression

Symbol Name
ANOS1 anosmin 1
AQP4 aquaporin 4
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNA2 cyclin A2
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CDCA4 cell division cycle associated 4
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLIC3 chloride intracellular channel 3
COL6A3 collagen, type VI, alpha 3
DDAH1 dimethylarginine dimethylaminohydrolase 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
FAM46A family with sequence similarity 46, member A
FKBP11 FK506 binding protein 11, 19 kDa
HK2 hexokinase 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP4 insulin-like growth factor binding protein 4
INHBA inhibin, beta A
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KIF20A kinesin family member 20A
LPCAT1 lysophosphatidylcholine acyltransferase 1
LUM lumican
MCM10 minichromosome maintenance complex component 10
MKI67 marker of proliferation Ki-67
MT1E metallothionein 1E
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAV3 neuron navigator 3
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUP98 nucleoporin 98kDa
ODC1 ornithine decarboxylase 1
PLAC8 placenta-specific 8
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTGER4 prostaglandin E receptor 4 (subtype EP4)
S100A6 S100 calcium binding protein A6
SATB1 SATB homeobox 1
SFRP4 secreted frizzled-related protein 4
SFTPB surfactant protein B
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SNX11 sorting nexin 11
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAGLN transgelin
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
ZNF22 zinc finger protein 22