BRD-K93788137_PF-431396_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K93788137_PF-431396_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDOB aldolase B, fructose-bisphosphate
BCL2A1 BCL2-related protein A1
C5AR1 complement component 5a receptor 1
CD14 CD14 molecule
CES1 carboxylesterase 1
COL9A3 collagen, type IX, alpha 3
CSTA cystatin A (stefin A)
CXCL8 chemokine (C-X-C motif) ligand 8
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
GPC3 glypican 3
GSN gelsolin
GSTA1 glutathione S-transferase alpha 1
IGFBP7 insulin-like growth factor binding protein 7
KLK11 kallikrein-related peptidase 11
KRT5 keratin 5, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MMP9 matrix metallopeptidase 9
MSLN mesothelin
NPR3 natriuretic peptide receptor 3
OAT ornithine aminotransferase
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLAGL1 pleiomorphic adenoma gene-like 1
PRSS21 protease, serine, 21 (testisin)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIK1 salt-inducible kinase 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPINK1 serine peptidase inhibitor, Kazal type 1
STOM stomatin
TCTA T-cell leukemia translocation altered
TF transferrin
TSPAN8 tetraspanin 8
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ASPH aspartate beta-hydroxylase
AURKA aurora kinase A
AURKB aurora kinase B
CDC25B cell division cycle 25B
CEMIP cell migration inducing protein, hyaluronan binding
EIF5 eukaryotic translation initiation factor 5
FZD7 frizzled class receptor 7
LINC00341 long intergenic non-protein coding RNA 341
LRRC8D leucine rich repeat containing 8 family, member D
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NNMT nicotinamide N-methyltransferase
PODXL podocalyxin-like
PSRC1 proline/serine-rich coiled-coil 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TRPS1 trichorhinophalangeal syndrome I