BRD-K93747373_HG-5-113-01_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K93747373_HG-5-113-01_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
BTG1 B-cell translocation gene 1, anti-proliferative
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEMIP cell migration inducing protein, hyaluronan binding
COMP cartilage oligomeric matrix protein
CRIP2 cysteine-rich protein 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
GJA1 gap junction protein, alpha 1, 43kDa
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HYAL1 hyaluronoglucosaminidase 1
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
ISG20 interferon stimulated exonuclease gene 20kDa
MSLN mesothelin
NDRG1 N-myc downstream regulated 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A12 S100 calcium binding protein A12
S100P S100 calcium binding protein P
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC38A1 solute carrier family 38, member 1
SPAG4 sperm associated antigen 4
SPON1 spondin 1, extracellular matrix protein
TFF1 trefoil factor 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
APOD apolipoprotein D
C2CD5 C2 calcium-dependent domain containing 5
CBX1 chromobox homolog 1
CCDC86 coiled-coil domain containing 86
COL6A2 collagen, type VI, alpha 2
CREB1 cAMP responsive element binding protein 1
CTSC cathepsin C
CXCL14 chemokine (C-X-C motif) ligand 14
CYB5A cytochrome b5 type A (microsomal)
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DPT dermatopontin
DPYSL3 dihydropyrimidinase-like 3
DST dystonin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FOLR1 folate receptor 1 (adult)
GALE UDP-galactose-4-epimerase
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GOLM1 golgi membrane protein 1
GYG2 glycogenin 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIF14 kinesin family member 14
PFN2 profilin 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLEKHA5 pleckstrin homology domain containing, family A member 5
QDPR quinoid dihydropteridine reductase
RAB38 RAB38, member RAS oncogene family
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP1 secreted frizzled-related protein 1
SNX10 sorting nexin 10
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPX sushi-repeat containing protein, X-linked
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZNF22 zinc finger protein 22