BRD-K93747373_HG-5-113-01_MDAMB231_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K93747373_HG-5-113-01_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLU clusterin
CXCL5 chemokine (C-X-C motif) ligand 5
FBN2 fibrillin 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GRB7 growth factor receptor-bound protein 7
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOPX HOP homeobox
KRT14 keratin 14, type I
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
NES nestin
PI3 peptidase inhibitor 3, skin-derived
PRAME preferentially expressed antigen in melanoma
RGCC regulator of cell cycle
TPD52 tumor protein D52
TSPAN6 tetraspanin 6

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ASPN asporin
BARD1 BRCA1 associated RING domain 1
CAST calpastatin
CBR3 carbonyl reductase 3
CENPU centromere protein U
CXCL14 chemokine (C-X-C motif) ligand 14
DPYSL2 dihydropyrimidinase-like 2
G0S2 G0/G1 switch 2
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP5 insulin-like growth factor binding protein 5
LYZ lysozyme
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MCUR1 mitochondrial calcium uniporter regulator 1
MYLK myosin light chain kinase
NREP neuronal regeneration related protein
PCM1 pericentriolar material 1
PLN phospholamban
POSTN periostin, osteoblast specific factor
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RPS11 ribosomal protein S11
RRM2 ribonucleotide reductase M2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
THBS1 thrombospondin 1
VCAN versican