BRD-K93747373_HG-5-113-01_HS578T_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K93747373_HG-5-113-01_HS578T_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AURKA aurora kinase A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CA12 carbonic anhydrase XII
CD36 CD36 molecule (thrombospondin receptor)
CD9 CD9 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CGA glycoprotein hormones, alpha polypeptide
CSRP2 cysteine and glycine-rich protein 2
DUSP6 dual specificity phosphatase 6
ESR1 estrogen receptor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
G0S2 G0/G1 switch 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GHR growth hormone receptor
GNB5 guanine nucleotide binding protein (G protein), beta 5
GSTA1 glutathione S-transferase alpha 1
H2BFS H2B histone family, member S (pseudogene)
H3F3B H3 histone, family 3B (H3.3B)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
ICAM3 intercellular adhesion molecule 3
ITGA6 integrin, alpha 6
JMJD6 jumonji domain containing 6
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
LPAR2 lysophosphatidic acid receptor 2
MX1 MX dynamin-like GTPase 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBP1 retinol binding protein 1, cellular
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SMTN smoothelin
SOX9 SRY (sex determining region Y)-box 9
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TSPAN13 tetraspanin 13
VAV3 vav 3 guanine nucleotide exchange factor
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AEBP1 AE binding protein 1
BIRC3 baculoviral IAP repeat containing 3
C1S complement component 1, s subcomponent
CHN1 chimerin 1
CIRBP cold inducible RNA binding protein
COL5A2 collagen, type V, alpha 2
CPD carboxypeptidase D
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTSK cathepsin K
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GTPBP8 GTP-binding protein 8 (putative)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGFBP7 insulin-like growth factor binding protein 7
IL1R1 interleukin 1 receptor, type I
IL6ST interleukin 6 signal transducer
LAMB1 laminin, beta 1
LAPTM4B lysosomal protein transmembrane 4 beta
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MMP7 matrix metallopeptidase 7
MOXD1 monooxygenase, DBH-like 1
MXRA5 matrix-remodelling associated 5
NPDC1 neural proliferation, differentiation and control, 1
PRAME preferentially expressed antigen in melanoma
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAD23B RAD23 homolog B (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SRSF6 serine/arginine-rich splicing factor 6
SULF1 sulfatase 1
TFDP1 transcription factor Dp-1
THY1 Thy-1 cell surface antigen
TMEM97 transmembrane protein 97
TP53 tumor protein p53
TSPAN4 tetraspanin 4
TSPYL5 TSPY-like 5
USP22 ubiquitin specific peptidase 22
VCAN versican