BRD-K93229693_2-(2-methoxyphenyl)-N-{4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl}acetamide_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K93229693_2-(2-methoxyphenyl)-N-{4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl}acetamide_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BTG1 B-cell translocation gene 1, anti-proliferative
CCL20 chemokine (C-C motif) ligand 20
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DSP desmoplakin
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IFI27 interferon, alpha-inducible protein 27
IGFBP3 insulin-like growth factor binding protein 3
IGKC immunoglobulin kappa constant
KLF4 Kruppel-like factor 4 (gut)
LCN2 lipocalin 2
LYZ lysozyme
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MFSD10 major facilitator superfamily domain containing 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
RHOB ras homolog family member B
SERINC5 serine incorporator 5
SST somatostatin
STEAP1 six transmembrane epithelial antigen of the prostate 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3

decreased expression

Symbol Name
DEPTOR DEP domain containing MTOR-interacting protein
GNAS GNAS complex locus
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
OXA1L oxidase (cytochrome c) assembly 1-like
TFF1 trefoil factor 1
TNC tenascin C
XIST X inactive specific transcript (non-protein coding)