BRD-K93123848_RAF 265_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K93123848_RAF 265_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
CARS cysteinyl-tRNA synthetase
CBS cystathionine-beta-synthase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
GARS glycyl-tRNA synthetase
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
NAMPT nicotinamide phosphoribosyltransferase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
XPOT exportin, tRNA

decreased expression

Symbol Name
CLU clusterin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
KCTD12 potassium channel tetramerization domain containing 12
KRAS Kirsten rat sarcoma viral oncogene homolog
LAPTM4B lysosomal protein transmembrane 4 beta
MT1X metallothionein 1X
RNASE4 ribonuclease, RNase A family, 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1B small proline-rich protein 1B
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)