BRD-K90382497_GW-843682X_SKBR3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

99 genes differentially expressed following the BRD-K90382497_GW-843682X_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
BMP2 bone morphogenetic protein 2
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CD24 CD24 molecule
CD38 CD38 molecule
CDC20 cell division cycle 20
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COTL1 coactosin-like F-actin binding protein 1
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL9 chemokine (C-X-C motif) ligand 9
DENND1B DENN/MADD domain containing 1B
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUOX2 dual oxidase 2
FERMT2 fermitin family member 2
FHL2 four and a half LIM domains 2
FOLR1 folate receptor 1 (adult)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GAL galanin/GMAP prepropeptide
GBP1 guanylate binding protein 1, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGN3 high mobility group nucleosomal binding domain 3
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
MYL9 myosin, light chain 9, regulatory
PDLIM4 PDZ and LIM domain 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLK1 polo-like kinase 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTRF polymerase I and transcript release factor
PYGL phosphorylase, glycogen, liver
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
TAGLN2 transgelin 2
TFF1 trefoil factor 1
THBS1 thrombospondin 1
TSPAN8 tetraspanin 8
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
TUBB6 tubulin, beta 6 class V
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UPP1 uridine phosphorylase 1

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
AQP3 aquaporin 3 (Gill blood group)
ATXN1 ataxin 1
BCL6 B-cell CLL/lymphoma 6
CD99 CD99 molecule
CHN1 chimerin 1
CLDN3 claudin 3
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COL6A3 collagen, type VI, alpha 3
CXCL14 chemokine (C-X-C motif) ligand 14
CYB5A cytochrome b5 type A (microsomal)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP2 dual specificity phosphatase 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FXYD3 FXYD domain containing ion transport regulator 3
GSTA4 glutathione S-transferase alpha 4
GUSBP3 glucuronidase, beta pseudogene 3
H2BFS H2B histone family, member S (pseudogene)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BK histone cluster 1, H2bk
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM2 interferon induced transmembrane protein 2
IGF1 insulin-like growth factor 1 (somatomedin C)
ISG15 ISG15 ubiquitin-like modifier
KDM5D lysine (K)-specific demethylase 5D
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC17 leucine rich repeat containing 17
MAOA monoamine oxidase A
MARCKSL1 MARCKS-like 1
MX2 MX dynamin-like GTPase 2
NAMPT nicotinamide phosphoribosyltransferase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PROM1 prominin 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A9 S100 calcium binding protein A9
SCAND1 SCAN domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
VLDLR very low density lipoprotein receptor
XBP1 X-box binding protein 1