BRD-K90382497_GW-843682X_SKBR3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K90382497_GW-843682X_SKBR3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
ANXA3 annexin A3
ARHGAP6 Rho GTPase activating protein 6
AURKA aurora kinase A
C1ORF106 chromosome 1 open reading frame 106
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC20 cell division cycle 20
CEMIP cell migration inducing protein, hyaluronan binding
CHN1 chimerin 1
COLEC12 collectin sub-family member 12
CPE carboxypeptidase E
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
CXCL11 chemokine (C-X-C motif) ligand 11
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DHRS2 dehydrogenase/reductase (SDR family) member 2
FN1 fibronectin 1
FSTL1 follistatin-like 1
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GHR growth hormone receptor
GLIPR1 GLI pathogenesis-related 1
GNAS GNAS complex locus
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JMJD6 jumonji domain containing 6
KIAA0226L KIAA0226-like
LMO3 LIM domain only 3 (rhombotin-like 2)
LPAR6 lysophosphatidic acid receptor 6
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCUR1 mitochondrial calcium uniporter regulator 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
NEFH neurofilament, heavy polypeptide
NPTX2 neuronal pentraxin II
NTS neurotensin
PAPD7 PAP associated domain containing 7
PFKP phosphofructokinase, platelet
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLIN2 perilipin 2
PLK1 polo-like kinase 1
PXDN peroxidasin
SEPP1 selenoprotein P, plasma, 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SMAD3 SMAD family member 3
SQRDL sulfide quinone reductase-like (yeast)
TFF1 trefoil factor 1
THBS1 thrombospondin 1
TPBG trophoblast glycoprotein
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
TUBB6 tubulin, beta 6 class V
TWIST1 twist family bHLH transcription factor 1
VCL vinculin
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANXA4 annexin A4
APOC2 apolipoprotein C-II
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BASP1 brain abundant, membrane attached signal protein 1
BDH2 3-hydroxybutyrate dehydrogenase, type 2
CLU clusterin
CREM cAMP responsive element modulator
CRIP1 cysteine-rich protein 1 (intestinal)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERBB3 erb-b2 receptor tyrosine kinase 3
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FXYD3 FXYD domain containing ion transport regulator 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GSTM3 glutathione S-transferase mu 3 (brain)
HIST1H2BK histone cluster 1, H2bk
KDM5D lysine (K)-specific demethylase 5D
KRT6B keratin 6B, type II
NDRG2 NDRG family member 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A9 S100 calcium binding protein A9
SFRP1 secreted frizzled-related protein 1
SPP1 secreted phosphoprotein 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TXNIP thioredoxin interacting protein
VLDLR very low density lipoprotein receptor
VTCN1 V-set domain containing T cell activation inhibitor 1
XBP1 X-box binding protein 1