BRD-K90382497_GW-843682X_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K90382497_GW-843682X_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
AURKA aurora kinase A
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CHL1 cell adhesion molecule L1-like
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EIF1 eukaryotic translation initiation factor 1
ELL2 elongation factor, RNA polymerase II, 2
FKBP11 FK506 binding protein 11, 19 kDa
GAL galanin/GMAP prepropeptide
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HMGA1 high mobility group AT-hook 1
ITM2A integral membrane protein 2A
KIAA0355 KIAA0355
KRT23 keratin 23, type I
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
RGS10 regulator of G-protein signaling 10
SCGB2A2 secretoglobin, family 2A, member 2
SEPP1 selenoprotein P, plasma, 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SOX9 SRY (sex determining region Y)-box 9
SSBP2 single-stranded DNA binding protein 2
TFPI2 tissue factor pathway inhibitor 2
TPM4 tropomyosin 4

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANO1 anoctamin 1, calcium activated chloride channel
ASPH aspartate beta-hydroxylase
CAT catalase
CCNE2 cyclin E2
CDK1 cyclin-dependent kinase 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSRP2 cysteine and glycine-rich protein 2
DDAH1 dimethylarginine dimethylaminohydrolase 1
DLD dihydrolipoamide dehydrogenase
EGFR epidermal growth factor receptor
EPS8 epidermal growth factor receptor pathway substrate 8
ETV1 ets variant 1
FANCL Fanconi anemia, complementation group L
HMGA2 high mobility group AT-hook 2
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KYNU kynureninase
LGALS3 lectin, galactoside-binding, soluble, 3
METTL7A methyltransferase like 7A
MMP1 matrix metallopeptidase 1
MTMR11 myotubularin related protein 11
PCP4 Purkinje cell protein 4
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
RAB31 RAB31, member RAS oncogene family
RAD51AP1 RAD51 associated protein 1
RNASE4 ribonuclease, RNase A family, 4
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
TACSTD2 tumor-associated calcium signal transducer 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIM2 tripartite motif containing 2
TST thiosulfate sulfurtransferase (rhodanese)