BRD-K90382497_GW-843682X_PC3_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K90382497_GW-843682X_PC3_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACSL1 acyl-CoA synthetase long-chain family member 1
AURKA aurora kinase A
BGN biglycan
CCNA1 cyclin A1
CD14 CD14 molecule
CD93 CD93 molecule
CGA glycoprotein hormones, alpha polypeptide
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
COL9A3 collagen, type IX, alpha 3
CXCL2 chemokine (C-X-C motif) ligand 2
CXCR4 chemokine (C-X-C motif) receptor 4
DAPK1 death-associated protein kinase 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
F13A1 coagulation factor XIII, A1 polypeptide
FGFR3 fibroblast growth factor receptor 3
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
GADD45B growth arrest and DNA-damage-inducible, beta
GAL galanin/GMAP prepropeptide
GLIPR1 GLI pathogenesis-related 1
H2BFS H2B histone family, member S (pseudogene)
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
ICAM2 intercellular adhesion molecule 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI30 interferon, gamma-inducible protein 30
KAZN kazrin, periplakin interacting protein
KIF20A kinesin family member 20A
KLF10 Kruppel-like factor 10
KLHDC10 kelch domain containing 10
KRT17 keratin 17, type I
KRT5 keratin 5, type II
MIR22HG MIR22 host gene
MTSS1 metastasis suppressor 1
NOTCH1 notch 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QDPR quinoid dihydropteridine reductase
RANBP2 RAN binding protein 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCG2 secretogranin II
SERINC5 serine incorporator 5
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIK1 salt-inducible kinase 1
STAB1 stabilin 1
TAGLN transgelin
THBS1 thrombospondin 1
VCAN versican
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA1 annexin A1
ASPH aspartate beta-hydroxylase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C1RL complement component 1, r subcomponent-like
CCNE2 cyclin E2
CDK1 cyclin-dependent kinase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CST7 cystatin F (leukocystatin)
CSTA cystatin A (stefin A)
ETV1 ets variant 1
FAM129A family with sequence similarity 129, member A
FAM162A family with sequence similarity 162, member A
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GBP2 guanylate binding protein 2, interferon-inducible
GOLGA8A golgin A8 family, member A
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPNMB glycoprotein (transmembrane) nmb
GREM1 gremlin 1, DAN family BMP antagonist
GSPT2 G1 to S phase transition 2
HIST1H4C histone cluster 1, H4c
HMGA2 high mobility group AT-hook 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
IFRD2 interferon-related developmental regulator 2
LUM lumican
MLPH melanophilin
MMP1 matrix metallopeptidase 1
PLAT plasminogen activator, tissue
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RAD51AP1 RAD51 associated protein 1
S100A7 S100 calcium binding protein A7
SCAND1 SCAN domain containing 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SPON2 spondin 2, extracellular matrix protein
SYNM synemin, intermediate filament protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNIK TRAF2 and NCK interacting kinase
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TST thiosulfate sulfurtransferase (rhodanese)
WEE1 WEE1 G2 checkpoint kinase
WNT5A wingless-type MMTV integration site family, member 5A