BRD-K90382497_GW-843682X_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K90382497_GW-843682X_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
CA2 carbonic anhydrase II
CD36 CD36 molecule (thrombospondin receptor)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYBRD1 cytochrome b reductase 1
EDN1 endothelin 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP4 fatty acid binding protein 4, adipocyte
FZD5 frizzled class receptor 5
GLIPR1 GLI pathogenesis-related 1
GNAS GNAS complex locus
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
KIAA0226L KIAA0226-like
KRT17 keratin 17, type I
LDHB lactate dehydrogenase B
NNMT nicotinamide N-methyltransferase
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NTS neurotensin
NUP98 nucleoporin 98kDa
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLK2 polo-like kinase 2
POSTN periostin, osteoblast specific factor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
S100P S100 calcium binding protein P
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLPI secretory leukocyte peptidase inhibitor
SRGN serglycin
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TPM4 tropomyosin 4
TUBB6 tubulin, beta 6 class V

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADGRG6 adhesion G protein-coupled receptor G6
ANO1 anoctamin 1, calcium activated chloride channel
AQP9 aquaporin 9
ARG1 arginase 1
ASCL1 achaete-scute family bHLH transcription factor 1
CCP110 centriolar coiled coil protein 110kDa
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DPP4 dipeptidyl-peptidase 4
DST dystonin
DTX4 deltex 4, E3 ubiquitin ligase
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETV1 ets variant 1
FBLN1 fibulin 1
FOXF1 forkhead box F1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GAS7 growth arrest-specific 7
HMGA2 high mobility group AT-hook 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
METTL7A methyltransferase like 7A
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PAM peptidylglycine alpha-amidating monooxygenase
PCP4 Purkinje cell protein 4
PTPRD protein tyrosine phosphatase, receptor type, D
PXDN peroxidasin
RAB31 RAB31, member RAS oncogene family
RGS17 regulator of G-protein signaling 17
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPDEF SAM pointed domain containing ETS transcription factor
STS steroid sulfatase (microsomal), isozyme S
SYNGR3 synaptogyrin 3
TOP2A topoisomerase (DNA) II alpha 170kDa
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)