BRD-K90382497_GW-843682X_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K90382497_GW-843682X_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ADCK3 aarF domain containing kinase 3
ANO1 anoctamin 1, calcium activated chloride channel
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDKN2A cyclin-dependent kinase inhibitor 2A
CFD complement factor D (adipsin)
CKB creatine kinase, brain
CLU clusterin
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
DARS aspartyl-tRNA synthetase
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DES desmin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DST dystonin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EPHA3 EPH receptor A3
F13A1 coagulation factor XIII, A1 polypeptide
FOXF1 forkhead box F1
GADD45A growth arrest and DNA-damage-inducible, alpha
HSPB8 heat shock 22kDa protein 8
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP1B microtubule-associated protein 1B
MEF2C myocyte enhancer factor 2C
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MTCL1 microtubule crosslinking factor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NUPR1 nuclear protein, transcriptional regulator, 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLS3 plastin 3
RAB40B RAB40B, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS1 regulator of G-protein signaling 1
S100P S100 calcium binding protein P
SCRG1 stimulator of chondrogenesis 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLIT2 slit homolog 2 (Drosophila)
TCF4 transcription factor 4
TPPP3 tubulin polymerization-promoting protein family member 3
TSC22D3 TSC22 domain family, member 3
TSPAN8 tetraspanin 8
TYMS thymidylate synthetase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
ADGRG6 adhesion G protein-coupled receptor G6
AIM1 absent in melanoma 1
ALDOB aldolase B, fructose-bisphosphate
ANXA1 annexin A1
AQP3 aquaporin 3 (Gill blood group)
C8ORF4 chromosome 8 open reading frame 4
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CAST calpastatin
CD52 CD52 molecule
CDC42 cell division cycle 42
COL3A1 collagen, type III, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXADR coxsackie virus and adenovirus receptor
DPYD dihydropyrimidine dehydrogenase
ECM1 extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
FASTKD5 FAST kinase domains 5
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FSTL1 follistatin-like 1
FZD2 frizzled class receptor 2
GATA2 GATA binding protein 2
GJA1 gap junction protein, alpha 1, 43kDa
GPRC5A G protein-coupled receptor, class C, group 5, member A
HACD3 3-hydroxyacyl-CoA dehydratase 3
HOPX HOP homeobox
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
LPCAT1 lysophosphatidylcholine acyltransferase 1
MALL mal, T-cell differentiation protein-like
MBOAT7 membrane bound O-acyltransferase domain containing 7
MEGF9 multiple EGF-like-domains 9
MRPS16 mitochondrial ribosomal protein S16
NOX4 NADPH oxidase 4
PALLD palladin, cytoskeletal associated protein
PCCB propionyl CoA carboxylase, beta polypeptide
PTGER4 prostaglandin E receptor 4 (subtype EP4)
S100A12 S100 calcium binding protein A12
SC5D sterol-C5-desaturase
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMCO4 single-pass membrane protein with coiled-coil domains 4
SUSD4 sushi domain containing 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TPD52L1 tumor protein D52-like 1
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
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