BRD-K90382497_GW-843682X_LNCAP_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K90382497_GW-843682X_LNCAP_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM2 absent in melanoma 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
CADM1 cell adhesion molecule 1
CAPN6 calpain 6
CCK cholecystokinin
CLDN10 claudin 10
COL4A2 collagen, type IV, alpha 2
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP22 dual specificity phosphatase 22
GRIA2 glutamate receptor, ionotropic, AMPA 2
H1F0 H1 histone family, member 0
HSPB8 heat shock 22kDa protein 8
ICAM1 intercellular adhesion molecule 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
IGFBP4 insulin-like growth factor binding protein 4
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNK3 potassium channel, two pore domain subfamily K, member 3
KRT19 keratin 19, type I
LEPROT leptin receptor overlapping transcript
LMO4 LIM domain only 4
MCAM melanoma cell adhesion molecule
MCOLN1 mucolipin 1
NPTX1 neuronal pentraxin I
OSBPL10 oxysterol binding protein-like 10
PCSK1 proprotein convertase subtilisin/kexin type 1
PDLIM4 PDZ and LIM domain 4
PDLIM5 PDZ and LIM domain 5
PRKCB protein kinase C, beta
RHOF ras homolog family member F (in filopodia)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100P S100 calcium binding protein P
SEPP1 selenoprotein P, plasma, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SNAP25 synaptosomal-associated protein, 25kDa
TESC tescalcin
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIB3 tribbles pseudokinase 3
TSPAN13 tetraspanin 13
TUBA4A tubulin, alpha 4a

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AIM1 absent in melanoma 1
BPHL biphenyl hydrolase-like (serine hydrolase)
CCL20 chemokine (C-C motif) ligand 20
CLCA2 chloride channel accessory 2
CRABP1 cellular retinoic acid binding protein 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DCN decorin
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
FBN2 fibrillin 2
FHL1 four and a half LIM domains 1
GCH1 GTP cyclohydrolase 1
GRK5 G protein-coupled receptor kinase 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
LINC00341 long intergenic non-protein coding RNA 341
LUM lumican
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NREP neuronal regeneration related protein
RIN2 Ras and Rab interactor 2
S100A8 S100 calcium binding protein A8
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCML1 sex comb on midleg-like 1 (Drosophila)
SDC1 syndecan 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SULF1 sulfatase 1
SYNM synemin, intermediate filament protein
THBS2 thrombospondin 2
TLR4 toll-like receptor 4
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM255A transmembrane protein 255A
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
VLDLR very low density lipoprotein receptor
VNN1 vanin 1