BRD-K90382497_GW-843682X_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K90382497_GW-843682X_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ANPEP alanyl (membrane) aminopeptidase
COL18A1 collagen, type XVIII, alpha 1
DCLK1 doublecortin-like kinase 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DHCR24 24-dehydrocholesterol reductase
DLK1 delta-like 1 homolog (Drosophila)
EPHB2 EPH receptor B2
FGF13 fibroblast growth factor 13
FGFR4 fibroblast growth factor receptor 4
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAL galanin/GMAP prepropeptide
HMG20B high mobility group 20B
ITGA6 integrin, alpha 6
JMJD6 jumonji domain containing 6
MEG3 maternally expressed 3 (non-protein coding)
OLFM4 olfactomedin 4
PAWR PRKC, apoptosis, WT1, regulator
PMP22 peripheral myelin protein 22
PRUNE2 prune homolog 2 (Drosophila)
PXDN peroxidasin
RGS1 regulator of G-protein signaling 1
SATB2 SATB homeobox 2
SCD5 stearoyl-CoA desaturase 5
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMYD3 SET and MYND domain containing 3
SNAI2 snail family zinc finger 2
SRPX sushi-repeat containing protein, X-linked
TNIK TRAF2 and NCK interacting kinase
UBE2S ubiquitin-conjugating enzyme E2S

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADM adrenomedullin
AKR1C3 aldo-keto reductase family 1, member C3
AQP3 aquaporin 3 (Gill blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BID BH3 interacting domain death agonist
C10ORF10 chromosome 10 open reading frame 10
C8ORF4 chromosome 8 open reading frame 4
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNF cyclin F
CD52 CD52 molecule
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EHD3 EH-domain containing 3
EIF5A eukaryotic translation initiation factor 5A
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GJA1 gap junction protein, alpha 1, 43kDa
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTM3 glutathione S-transferase mu 3 (brain)
HBB hemoglobin, beta
HILPDA hypoxia inducible lipid droplet-associated
HOPX HOP homeobox
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL32 interleukin 32
ISG20 interferon stimulated exonuclease gene 20kDa
KRT7 keratin 7, type II
MELK maternal embryonic leucine zipper kinase
MSH6 mutS homolog 6
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NAMPT nicotinamide phosphoribosyltransferase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRIP1 nuclear receptor interacting protein 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCNA proliferating cell nuclear antigen
PLIN2 perilipin 2
PRAME preferentially expressed antigen in melanoma
QPCT glutaminyl-peptide cyclotransferase
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RPS4Y1 ribosomal protein S4, Y-linked 1
RRM2 ribonucleotide reductase M2
SDC4 syndecan 4
SOX4 SRY (sex determining region Y)-box 4
STAT1 signal transducer and activator of transcription 1, 91kDa
TFPI2 tissue factor pathway inhibitor 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TXNDC9 thioredoxin domain containing 9
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VNN1 vanin 1
WEE1 WEE1 G2 checkpoint kinase