BRD-K90382497_GW-843682X_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K90382497_GW-843682X_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ANPEP alanyl (membrane) aminopeptidase
AURKA aurora kinase A
BHLHE40 basic helix-loop-helix family, member e40
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CDC20 cell division cycle 20
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTSC cathepsin C
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLC1 DLC1 Rho GTPase activating protein
FGFR3 fibroblast growth factor receptor 3
FOSL1 FOS-like antigen 1
GAL galanin/GMAP prepropeptide
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
ITGA6 integrin, alpha 6
JCHAIN joining chain of multimeric IgA and IgM
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NELL2 NEL-like 2 (chicken)
NNMT nicotinamide N-methyltransferase
NPC1 Niemann-Pick disease, type C1
NPTX2 neuronal pentraxin II
P3H2 prolyl 3-hydroxylase 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PFKP phosphofructokinase, platelet
PODXL podocalyxin-like
POSTN periostin, osteoblast specific factor
POU2AF1 POU class 2 associating factor 1
PRMT1 protein arginine methyltransferase 1
RGS1 regulator of G-protein signaling 1
SELL selectin L
STEAP3 STEAP family member 3, metalloreductase
TARP TCR gamma alternate reading frame protein
TBX2 T-box 2
TCL1A T-cell leukemia/lymphoma 1A
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TUBB2A tubulin, beta 2A class IIa
VWF von Willebrand factor
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ANO1 anoctamin 1, calcium activated chloride channel
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CALD1 caldesmon 1
CCNE2 cyclin E2
CD44 CD44 molecule (Indian blood group)
CDK1 cyclin-dependent kinase 1
CFLAR CASP8 and FADD-like apoptosis regulator
CTBP2 C-terminal binding protein 2
CTSB cathepsin B
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP6 dual specificity phosphatase 6
EMP1 epithelial membrane protein 1
EXOSC4 exosome component 4
F5 coagulation factor V (proaccelerin, labile factor)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GAS7 growth arrest-specific 7
GPRC5A G protein-coupled receptor, class C, group 5, member A
HOXA10 homeobox A10
HOXA5 homeobox A5
HSPA1A heat shock 70kDa protein 1A
KRT19 keratin 19, type I
LOC100272216 uncharacterized LOC100272216
LTBP3 latent transforming growth factor beta binding protein 3
MANSC1 MANSC domain containing 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NET1 neuroepithelial cell transforming 1
NRIP1 nuclear receptor interacting protein 1
PALLD palladin, cytoskeletal associated protein
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RNMT RNA (guanine-7-) methyltransferase
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
TBX3 T-box 3
TMEM45A transmembrane protein 45A
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
WEE1 WEE1 G2 checkpoint kinase
ZFP36L2 ZFP36 ring finger protein-like 2