BRD-K90382497_GW-843682X_HT29_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K90382497_GW-843682X_HT29_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ANPEP alanyl (membrane) aminopeptidase
AURKA aurora kinase A
C6ORF62 chromosome 6 open reading frame 62
CERS6 ceramide synthase 6
CHRDL1 chordin-like 1
COL13A1 collagen, type XIII, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
DLK1 delta-like 1 homolog (Drosophila)
DMBT1 deleted in malignant brain tumors 1
EPHB2 EPH receptor B2
FAM117A family with sequence similarity 117, member A
FAM46A family with sequence similarity 46, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FHL1 four and a half LIM domains 1
FOSL1 FOS-like antigen 1
HPCAL1 hippocalcin-like 1
IGFBP7 insulin-like growth factor binding protein 7
ITGA6 integrin, alpha 6
ITGB1BP1 integrin beta 1 binding protein 1
JADE2 jade family PHD finger 2
MT1E metallothionein 1E
NELL2 NEL-like 2 (chicken)
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
PMP22 peripheral myelin protein 22
RGS1 regulator of G-protein signaling 1
RPS11 ribosomal protein S11
RPS21 ribosomal protein S21
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNIK TRAF2 and NCK interacting kinase
TOB1 transducer of ERBB2, 1
TOX3 TOX high mobility group box family member 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
UBE2S ubiquitin-conjugating enzyme E2S
ZBTB18 zinc finger and BTB domain containing 18
ZNF652 zinc finger protein 652
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMIGO2 adhesion molecule with Ig-like domain 2
ANO1 anoctamin 1, calcium activated chloride channel
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BHLHE41 basic helix-loop-helix family, member e41
C10ORF10 chromosome 10 open reading frame 10
CA12 carbonic anhydrase XII
CCL5 chemokine (C-C motif) ligand 5
CD200 CD200 molecule
CD24 CD24 molecule
CDK1 cyclin-dependent kinase 1
CXCL5 chemokine (C-X-C motif) ligand 5
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
ESR1 estrogen receptor 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBB hemoglobin, beta
HILPDA hypoxia inducible lipid droplet-associated
HMGA2 high mobility group AT-hook 2
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IRS1 insulin receptor substrate 1
ISG20 interferon stimulated exonuclease gene 20kDa
KIAA0101 KIAA0101
KRT13 keratin 13, type I
KRT23 keratin 23, type I
MDK midkine (neurite growth-promoting factor 2)
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
PCNA proliferating cell nuclear antigen
POU2AF1 POU class 2 associating factor 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSD3 pleckstrin and Sec7 domain containing 3
RNMT RNA (guanine-7-) methyltransferase
RRM2 ribonucleotide reductase M2
SAT1 spermidine/spermine N1-acetyltransferase 1
SFRP4 secreted frizzled-related protein 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SPEN spen family transcriptional repressor
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
VCAM1 vascular cell adhesion molecule 1
VLDLR very low density lipoprotein receptor
WWTR1 WW domain containing transcription regulator 1