BRD-K90382497_GW-843682X_HME1_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K90382497_GW-843682X_HME1_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BCL3 B-cell CLL/lymphoma 3
CADM1 cell adhesion molecule 1
CD83 CD83 molecule
COL9A3 collagen, type IX, alpha 3
COMP cartilage oligomeric matrix protein
CSAD cysteine sulfinic acid decarboxylase
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP5 dual specificity phosphatase 5
EHD1 EH-domain containing 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
G0S2 G0/G1 switch 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
ICAM1 intercellular adhesion molecule 1
IFI6 interferon, alpha-inducible protein 6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IRF1 interferon regulatory factor 1
KLF10 Kruppel-like factor 10
KRT19 keratin 19, type I
MAMLD1 mastermind-like domain containing 1
MT1M metallothionein 1M
MX1 MX dynamin-like GTPase 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLAUR plasminogen activator, urokinase receptor
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL10 ribosomal protein L10
RSRP1 arginine/serine-rich protein 1
S100B S100 calcium binding protein B
SDC4 syndecan 4
SRSF7 serine/arginine-rich splicing factor 7
STX1A syntaxin 1A (brain)
TFPI2 tissue factor pathway inhibitor 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSC22D3 TSC22 domain family, member 3
TWIST1 twist family bHLH transcription factor 1
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIM1 absent in melanoma 1
AKR1C2 aldo-keto reductase family 1, member C2
ASCL1 achaete-scute family bHLH transcription factor 1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
C14ORF132 chromosome 14 open reading frame 132
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLCA4 chloride channel accessory 4
COL4A6 collagen, type IV, alpha 6
CPB1 carboxypeptidase B1 (tissue)
CRCT1 cysteine-rich C-terminal 1
DENND1A DENN/MADD domain containing 1A
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FZD7 frizzled class receptor 7
HEPH hephaestin
HHEX hematopoietically expressed homeobox
HOXA5 homeobox A5
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL7R interleukin 7 receptor
IVL involucrin
LEPROTL1 leptin receptor overlapping transcript-like 1
LRRC17 leucine rich repeat containing 17
MDK midkine (neurite growth-promoting factor 2)
MTCL1 microtubule crosslinking factor 1
MTUS1 microtubule associated tumor suppressor 1
NCK1 NCK adaptor protein 1
PI3 peptidase inhibitor 3, skin-derived
PLCB4 phospholipase C, beta 4
RRAGD Ras-related GTP binding D
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERINC5 serine incorporator 5
SFRP1 secreted frizzled-related protein 1
SNAP25 synaptosomal-associated protein, 25kDa
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRR3 small proline-rich protein 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
VCAN versican
ZNF292 zinc finger protein 292