BRD-K90382497_GW-843682X_BT20_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K90382497_GW-843682X_BT20_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CADM1 cell adhesion molecule 1
DPP4 dipeptidyl-peptidase 4
DUSP6 dual specificity phosphatase 6
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FKBP14 FK506 binding protein 14, 22 kDa
GLDC glycine dehydrogenase (decarboxylating)
LAPTM4B lysosomal protein transmembrane 4 beta
MDK midkine (neurite growth-promoting factor 2)
NRGN neurogranin (protein kinase C substrate, RC3)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
TRPS1 trichorhinophalangeal syndrome I
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
CA2 carbonic anhydrase II
CD24 CD24 molecule
CHPT1 choline phosphotransferase 1
COG7 component of oligomeric golgi complex 7
EZR ezrin
FHL1 four and a half LIM domains 1
HIST1H2BK histone cluster 1, H2bk
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
MEF2C myocyte enhancer factor 2C
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
S100P S100 calcium binding protein P
SOX9 SRY (sex determining region Y)-box 9
SRSF6 serine/arginine-rich splicing factor 6
TCF4 transcription factor 4