BRD-K90382497_GW-843682X_BT20_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K90382497_GW-843682X_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATF4 activating transcription factor 4
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BANK1 B-cell scaffold protein with ankyrin repeats 1
CARS cysteinyl-tRNA synthetase
CDA cytidine deaminase
CRYAB crystallin, alpha B
CXCL14 chemokine (C-X-C motif) ligand 14
DAPK1 death-associated protein kinase 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DUSP22 dual specificity phosphatase 22
EIF5 eukaryotic translation initiation factor 5
FAM117A family with sequence similarity 117, member A
FOXO1 forkhead box O1
GADD45B growth arrest and DNA-damage-inducible, beta
GJA1 gap junction protein, alpha 1, 43kDa
GOLGA8A golgin A8 family, member A
GSAP gamma-secretase activating protein
HMG20B high mobility group 20B
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
MALL mal, T-cell differentiation protein-like
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSN moesin
MSX1 msh homeobox 1
MTCL1 microtubule crosslinking factor 1
MYOF myoferlin
NES nestin
NNMT nicotinamide N-methyltransferase
NXN nucleoredoxin
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PDLIM1 PDZ and LIM domain 1
PPIE peptidylprolyl isomerase E (cyclophilin E)
PRKCQ protein kinase C, theta
PYCR1 pyrroline-5-carboxylate reductase 1
RBM6 RNA binding motif protein 6
REXO2 RNA exonuclease 2
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TNNT1 troponin T type 1 (skeletal, slow)
TSKU tsukushi, small leucine rich proteoglycan
VEGFA vascular endothelial growth factor A
XAF1 XIAP associated factor 1

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ADGRG2 adhesion G protein-coupled receptor G2
AHR aryl hydrocarbon receptor
ALDOB aldolase B, fructose-bisphosphate
ANPEP alanyl (membrane) aminopeptidase
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CCNE2 cyclin E2
CDCA4 cell division cycle associated 4
CPE carboxypeptidase E
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FN1 fibronectin 1
GLUL glutamate-ammonia ligase
GPR137B G protein-coupled receptor 137B
HACD2 3-hydroxyacyl-CoA dehydratase 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMOX1 heme oxygenase 1
IFNGR1 interferon gamma receptor 1
IL13RA1 interleukin 13 receptor, alpha 1
KIF1BP KIF1 binding protein
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MDK midkine (neurite growth-promoting factor 2)
MPO myeloperoxidase
MSH6 mutS homolog 6
MYH11 myosin, heavy chain 11, smooth muscle
PNMA1 paraneoplastic Ma antigen 1
REG1A regenerating islet-derived 1 alpha
RFC5 replication factor C (activator 1) 5, 36.5kDa
RRM2 ribonucleotide reductase M2
SCAND1 SCAN domain containing 1
SERINC5 serine incorporator 5
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
STC1 stanniocalcin 1
TFDP1 transcription factor Dp-1
TFRC transferrin receptor
TMX4 thioredoxin-related transmembrane protein 4
TP53 tumor protein p53
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28