BRD-K90382497_GW-843682X_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K90382497_GW-843682X_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA3 annexin A3
ATF3 activating transcription factor 3
C5AR1 complement component 5a receptor 1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CSRP1 cysteine and glycine-rich protein 1
CXCL13 chemokine (C-X-C motif) ligand 13
CYR61 cysteine-rich, angiogenic inducer, 61
EGR1 early growth response 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GBP1 guanylate binding protein 1, interferon-inducible
GRB10 growth factor receptor-bound protein 10
HOPX HOP homeobox
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100505650 uncharacterized LOC100505650
MCL1 myeloid cell leukemia 1
MLF1 myeloid leukemia factor 1
MT1E metallothionein 1E
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PEA15 phosphoprotein enriched in astrocytes 15
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAUR plasminogen activator, urokinase receptor
PODXL podocalyxin-like
PRSS21 protease, serine, 21 (testisin)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100A2 S100 calcium binding protein A2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFN stratifin
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
STAR steroidogenic acute regulatory protein
TCF4 transcription factor 4
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALOX5 arachidonate 5-lipoxygenase
AQP3 aquaporin 3 (Gill blood group)
C14ORF132 chromosome 14 open reading frame 132
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CDC25B cell division cycle 25B
CDK1 cyclin-dependent kinase 1
CHPT1 choline phosphotransferase 1
COL6A3 collagen, type VI, alpha 3
CPD carboxypeptidase D
CPE carboxypeptidase E
CXCL12 chemokine (C-X-C motif) ligand 12
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
E2F2 E2F transcription factor 2
FCGBP Fc fragment of IgG binding protein
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
GPX3 glutathione peroxidase 3
HADH hydroxyacyl-CoA dehydrogenase
HILPDA hypoxia inducible lipid droplet-associated
HSPA1A heat shock 70kDa protein 1A
IGFBP5 insulin-like growth factor binding protein 5
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
MDK midkine (neurite growth-promoting factor 2)
MKI67 marker of proliferation Ki-67
MYO1B myosin IB
OLFML3 olfactomedin-like 3
PCP4 Purkinje cell protein 4
PTGER4 prostaglandin E receptor 4 (subtype EP4)
REEP1 receptor accessory protein 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
STC1 stanniocalcin 1
SVIL supervillin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR3 transforming growth factor, beta receptor III
TIAM1 T-cell lymphoma invasion and metastasis 1
TMX4 thioredoxin-related transmembrane protein 4
TP53TG1 TP53 target 1 (non-protein coding)
TPD52L1 tumor protein D52-like 1
UBE2C ubiquitin-conjugating enzyme E2C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
VTCN1 V-set domain containing T cell activation inhibitor 1