BRD-K90259198_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K90259198_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ARMCX2 armadillo repeat containing, X-linked 2
CAV1 caveolin 1, caveolae protein, 22kDa
CCND3 cyclin D3
CD40 CD40 molecule, TNF receptor superfamily member 5
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK14 cyclin-dependent kinase 14
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CTBP2 C-terminal binding protein 2
DENND1B DENN/MADD domain containing 1B
DIO1 deiodinase, iodothyronine, type I
EZR ezrin
FBXL5 F-box and leucine-rich repeat protein 5
FTH1 ferritin, heavy polypeptide 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GAS6 growth arrest-specific 6
GREM1 gremlin 1, DAN family BMP antagonist
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
HSPA2 heat shock 70kDa protein 2
IQGAP1 IQ motif containing GTPase activating protein 1
IVNS1ABP influenza virus NS1A binding protein
LPAR2 lysophosphatidic acid receptor 2
LRMP lymphoid-restricted membrane protein
LRP2 low density lipoprotein receptor-related protein 2
MAP7 microtubule-associated protein 7
MSLN mesothelin
NR1H2 nuclear receptor subfamily 1, group H, member 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPAP2B phosphatidic acid phosphatase type 2B
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERINC5 serine incorporator 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPON1 spondin 1, extracellular matrix protein
STAR steroidogenic acute regulatory protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM30B transmembrane protein 30B
TPD52L1 tumor protein D52-like 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1

decreased expression

Symbol Name
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
CDC123 cell division cycle 123
COL9A3 collagen, type IX, alpha 3
GLS glutaminase
GNAS GNAS complex locus
GRB14 growth factor receptor-bound protein 14
HN1 hematological and neurological expressed 1
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
PFN2 profilin 2
PLAC8 placenta-specific 8
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
TSPAN3 tetraspanin 3
TSPAN8 tetraspanin 8
VAT1 vesicle amine transport 1