BRD-K89329876_-666_VCAP_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K89329876_-666_VCAP_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
C5ORF30 chromosome 5 open reading frame 30
CAST calpastatin
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL3A1 collagen, type III, alpha 1
CST3 cystatin C
DSP desmoplakin
DYNLT3 dynein, light chain, Tctex-type 3
FGF13 fibroblast growth factor 13
GATA2 GATA binding protein 2
GLRX glutaredoxin (thioltransferase)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
LYN LYN proto-oncogene, Src family tyrosine kinase
PERP PERP, TP53 apoptosis effector
RGS2 regulator of G-protein signaling 2
RPS11 ribosomal protein S11
S100P S100 calcium binding protein P
SGK1 serum/glucocorticoid regulated kinase 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
STX1A syntaxin 1A (brain)
TMSB15A thymosin beta 15a
TRIB1 tribbles pseudokinase 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C1ORF116 chromosome 1 open reading frame 116
C3 complement component 3
CD93 CD93 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
COL10A1 collagen, type X, alpha 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ETV5 ets variant 5
FADS1 fatty acid desaturase 1
FGFBP1 fibroblast growth factor binding protein 1
HIST1H2BD histone cluster 1, H2bd
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HTRA1 HtrA serine peptidase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
LAMP3 lysosomal-associated membrane protein 3
LAPTM5 lysosomal protein transmembrane 5
MDK midkine (neurite growth-promoting factor 2)
MT1E metallothionein 1E
MT1X metallothionein 1X
MX1 MX dynamin-like GTPase 1
NMU neuromedin U
PDGFRL platelet-derived growth factor receptor-like
PEG10 paternally expressed 10
PLN phospholamban
PRKCDBP protein kinase C, delta binding protein
PYCARD PYD and CARD domain containing
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC43A3 solute carrier family 43, member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNS1 tensin 1