BRD-K88784410_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K88784410_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BASP1 brain abundant, membrane attached signal protein 1
CCNA1 cyclin A1
CD200 CD200 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EGR3 early growth response 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FOSL1 FOS-like antigen 1
HES1 hes family bHLH transcription factor 1
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KRT18 keratin 18, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NEFH neurofilament, heavy polypeptide
NGRN neugrin, neurite outgrowth associated
NT5E 5'-nucleotidase, ecto (CD73)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
THBS1 thrombospondin 1
TJP2 tight junction protein 2
TUSC3 tumor suppressor candidate 3
USP6NL USP6 N-terminal like

decreased expression

Symbol Name
AK4 adenylate kinase 4
ASS1 argininosuccinate synthase 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
C1S complement component 1, s subcomponent
C2CD5 C2 calcium-dependent domain containing 5
C7 complement component 7
CDCA4 cell division cycle associated 4
COL1A2 collagen, type I, alpha 2
DCN decorin
DMD dystrophin
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENSA endosulfine alpha
GLUL glutamate-ammonia ligase
GUSBP11 glucuronidase, beta pseudogene 11
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IQGAP2 IQ motif containing GTPase activating protein 2
KIF20A kinesin family member 20A
MCAM melanoma cell adhesion molecule
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTMR11 myotubularin related protein 11
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
PEG3 paternally expressed 3
PER2 period circadian clock 2
PRKCA protein kinase C, alpha
QPRT quinolinate phosphoribosyltransferase
RNASE6 ribonuclease, RNase A family, k6
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STOM stomatin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPM4 tropomyosin 4