BRD-K88625236_NONOXYNOL-9_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K88625236_NONOXYNOL-9_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
AGR2 anterior gradient 2
ALDOC aldolase C, fructose-bisphosphate
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA2 carbonic anhydrase II
CAPG capping protein (actin filament), gelsolin-like
CARS cysteinyl-tRNA synthetase
CBS cystathionine-beta-synthase
CCL4 chemokine (C-C motif) ligand 4
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GARS glycyl-tRNA synthetase
GPM6B glycoprotein M6B
GTPBP2 GTP binding protein 2
H1F0 H1 histone family, member 0
HBB hemoglobin, beta
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
MALL mal, T-cell differentiation protein-like
MAN2A1 mannosidase, alpha, class 2A, member 1
MINK1 misshapen-like kinase 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHGDH phosphoglycerate dehydrogenase
PLIN2 perilipin 2
PSAT1 phosphoserine aminotransferase 1
RIOK3 RIO kinase 3
SARS seryl-tRNA synthetase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
STC2 stanniocalcin 2
TGFA transforming growth factor, alpha
TNIP1 TNFAIP3 interacting protein 1
TRIB3 tribbles pseudokinase 3
TST thiosulfate sulfurtransferase (rhodanese)
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
CCNA2 cyclin A2
CLU clusterin
CNN3 calponin 3, acidic
COX11 COX11 cytochrome c oxidase copper chaperone
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GMNN geminin, DNA replication inhibitor
HOXC6 homeobox C6
HSPA8 heat shock 70kDa protein 8
KIF20A kinesin family member 20A
MRPL3 mitochondrial ribosomal protein L3
NR2F2 nuclear receptor subfamily 2, group F, member 2
OLFM1 olfactomedin 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SMYD2 SET and MYND domain containing 2
SYBU syntabulin (syntaxin-interacting)
TMEM5 transmembrane protein 5
TMEM97 transmembrane protein 97
TUBB2A tubulin, beta 2A class IIa