BRD-K88544581_CI 976_SW620_6.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K88544581_CI 976_SW620_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLDN7 claudin 7
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CRABP2 cellular retinoic acid binding protein 2
CRELD2 cysteine-rich with EGF-like domains 2
DENND1B DENN/MADD domain containing 1B
ECM1 extracellular matrix protein 1
FAP fibroblast activation protein, alpha
GAS1 growth arrest-specific 1
HEPH hephaestin
KIAA0753 KIAA0753
LOC100272216 uncharacterized LOC100272216
LRRC15 leucine rich repeat containing 15
MMP11 matrix metallopeptidase 11
MMP3 matrix metallopeptidase 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PLAU plasminogen activator, urokinase
POSTN periostin, osteoblast specific factor
PXDN peroxidasin
SARS seryl-tRNA synthetase
SULF1 sulfatase 1
TPBG trophoblast glycoprotein
TUSC3 tumor suppressor candidate 3
TWIST1 twist family bHLH transcription factor 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
C3 complement component 3
CCL19 chemokine (C-C motif) ligand 19
CDK6 cyclin-dependent kinase 6
CHMP4A charged multivesicular body protein 4A
CHPT1 choline phosphotransferase 1
CLU clusterin
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
FABP7 fatty acid binding protein 7, brain
GNAS GNAS complex locus
GPX3 glutathione peroxidase 3
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IGFBP4 insulin-like growth factor binding protein 4
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KAZN kazrin, periplakin interacting protein
MGLL monoglyceride lipase
NEFH neurofilament, heavy polypeptide
NNMT nicotinamide N-methyltransferase
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PLK1 polo-like kinase 1
PTDSS1 phosphatidylserine synthase 1
RFC5 replication factor C (activator 1) 5, 36.5kDa
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TGM2 transglutaminase 2
TMX4 thioredoxin-related transmembrane protein 4
VWF von Willebrand factor