BRD-K88544581_CI 976_PC3_6.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K88544581_CI 976_PC3_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
APOD apolipoprotein D
CSTA cystatin A (stefin A)
CXCL10 chemokine (C-X-C motif) ligand 10
DDIT4 DNA-damage-inducible transcript 4
HMOX1 heme oxygenase 1
HOXB7 homeobox B7
KLF4 Kruppel-like factor 4 (gut)
NRIP1 nuclear receptor interacting protein 1
SFN stratifin
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SNX10 sorting nexin 10
SOD2 superoxide dismutase 2, mitochondrial
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TMEM176B transmembrane protein 176B
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TUBB2A tubulin, beta 2A class IIa
VCAM1 vascular cell adhesion molecule 1
VGLL4 vestigial-like family member 4

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
C7 complement component 7
CD24 CD24 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
COL14A1 collagen, type XIV, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
DEFB1 defensin, beta 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
HAT1 histone acetyltransferase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
KLHL9 kelch-like family member 9
KRT7 keratin 7, type II
LBH limb bud and heart development
MDFIC MyoD family inhibitor domain containing
SORL1 sortilin-related receptor, L(DLR class) A repeats containing