BRD-K88544581_CI 976_PC3_24.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K88544581_CI 976_PC3_24.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ASS1 argininosuccinate synthase 1
BASP1 brain abundant, membrane attached signal protein 1
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
CBS cystathionine-beta-synthase
CCL4 chemokine (C-C motif) ligand 4
CLIC4 chloride intracellular channel 4
DDIT4 DNA-damage-inducible transcript 4
DUSP5 dual specificity phosphatase 5
FADS1 fatty acid desaturase 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
IL1B interleukin 1, beta
IL7R interleukin 7 receptor
MGLL monoglyceride lipase
MMP1 matrix metallopeptidase 1
MTMR11 myotubularin related protein 11
NDRG1 N-myc downstream regulated 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
RAB29 RAB29, member RAS oncogene family
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
TNIP1 TNFAIP3 interacting protein 1

decreased expression

Symbol Name
CDC45 cell division cycle 45
CYR61 cysteine-rich, angiogenic inducer, 61
FASTKD5 FAST kinase domains 5
HHEX hematopoietically expressed homeobox
ITM2A integral membrane protein 2A
PWP1 PWP1 homolog (S. cerevisiae)
SCG2 secretogranin II
SEPP1 selenoprotein P, plasma, 1
STK38L serine/threonine kinase 38 like
TIMP3 TIMP metallopeptidase inhibitor 3