BRD-K88544581_CI 976_A375_6.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

11 genes differentially expressed following the BRD-K88544581_CI 976_A375_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTB actin, beta
CARS cysteinyl-tRNA synthetase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
KLF4 Kruppel-like factor 4 (gut)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
KRT19 keratin 19, type I
NID2 nidogen 2 (osteonidogen)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1