BRD-K88378636_withaferin-a_LNCAP_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

90 genes differentially expressed following the BRD-K88378636_withaferin-a_LNCAP_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
AGR2 anterior gradient 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BAG3 BCL2-associated athanogene 3
CAST calpastatin
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL9A3 collagen, type IX, alpha 3
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
FGFR3 fibroblast growth factor receptor 3
GCLM glutamate-cysteine ligase, modifier subunit
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IGHM immunoglobulin heavy constant mu
ITGA6 integrin, alpha 6
JMJD6 jumonji domain containing 6
JUNB jun B proto-oncogene
KDM5A lysine (K)-specific demethylase 5A
KRT19 keratin 19, type I
KRT6A keratin 6A, type II
MAP7 microtubule-associated protein 7
MAST4 microtubule associated serine/threonine kinase family member 4
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEF2C myocyte enhancer factor 2C
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
PCDH9 protocadherin 9
PECAM1 platelet/endothelial cell adhesion molecule 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKD2 protein kinase D2
RABEP2 rabaptin, RAB GTPase binding effector protein 2
S100A14 S100 calcium binding protein A14
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TRIB3 tribbles pseudokinase 3
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARMCX2 armadillo repeat containing, X-linked 2
CCL20 chemokine (C-C motif) ligand 20
CLDN3 claudin 3
CPM carboxypeptidase M
CTSK cathepsin K
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
EGFR epidermal growth factor receptor
FOLR1 folate receptor 1 (adult)
FUS FUS RNA binding protein
GBP1 guanylate binding protein 1, interferon-inducible
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC17 leucine rich repeat containing 17
LTF lactotransferrin
NCK1 NCK adaptor protein 1
NPTN neuroplastin
PCP4 Purkinje cell protein 4
PDE9A phosphodiesterase 9A
PDGFRL platelet-derived growth factor receptor-like
PDIA3 protein disulfide isomerase family A, member 3
PEG10 paternally expressed 10
POSTN periostin, osteoblast specific factor
RNF167 ring finger protein 167
SCG2 secretogranin II
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SNAP25 synaptosomal-associated protein, 25kDa
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SULF1 sulfatase 1
TMPRSS3 transmembrane protease, serine 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNS1 tensin 1
WT1 Wilms tumor 1