BRD-K88198340_2-(6,6-dimethoxy-3-oxocyclohexa-1,4-dienylcarbamoyl)phenyl acetate GNFk-3_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K88198340_2-(6,6-dimethoxy-3-oxocyclohexa-1,4-dienylcarbamoyl)phenyl acetate GNFk-3_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C6ORF62 chromosome 6 open reading frame 62
CD36 CD36 molecule (thrombospondin receptor)
CD9 CD9 molecule
COL9A3 collagen, type IX, alpha 3
CTSB cathepsin B
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FHL2 four and a half LIM domains 2
FOLR1 folate receptor 1 (adult)
GSAP gamma-secretase activating protein
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGL immunoglobulin lambda locus
IGLL1 immunoglobulin lambda-like polypeptide 1
INPP1 inositol polyphosphate-1-phosphatase
JMJD6 jumonji domain containing 6
KRCC1 lysine-rich coiled-coil 1
KRT13 keratin 13, type I
LMO4 LIM domain only 4
NMU neuromedin U
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPTX2 neuronal pentraxin II
PPP1R15A protein phosphatase 1, regulatory subunit 15A
S100A2 S100 calcium binding protein A2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TUBB2A tubulin, beta 2A class IIa
WT1 Wilms tumor 1
XK X-linked Kx blood group
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ARHGAP29 Rho GTPase activating protein 29
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL2 chemokine (C-C motif) ligand 2
CD24 CD24 molecule
CD93 CD93 molecule
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DDIT4 DNA-damage-inducible transcript 4
DPYSL2 dihydropyrimidinase-like 2
DPYSL3 dihydropyrimidinase-like 3
EDNRA endothelin receptor type A
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM107A family with sequence similarity 107, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
GJA1 gap junction protein, alpha 1, 43kDa
IGFBP5 insulin-like growth factor binding protein 5
INHBB inhibin, beta B
KRT7 keratin 7, type II
LIMCH1 LIM and calponin homology domains 1
LITAF lipopolysaccharide-induced TNF factor
P3H2 prolyl 3-hydroxylase 2
PDZRN3 PDZ domain containing ring finger 3
PEG10 paternally expressed 10
PRKCH protein kinase C, eta
PSG5 pregnancy specific beta-1-glycoprotein 5
SDC2 syndecan 2
SGK1 serum/glucocorticoid regulated kinase 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TCF4 transcription factor 4
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNS3 tensin 3
TRIM2 tripartite motif containing 2
WNT5A wingless-type MMTV integration site family, member 5A