BRD-K88198340_2-(6,6-dimethoxy-3-oxocyclohexa-1,4-dienylcarbamoyl)phenyl acetate GNFk-3_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

112 genes differentially expressed following the BRD-K88198340_2-(6,6-dimethoxy-3-oxocyclohexa-1,4-dienylcarbamoyl)phenyl acetate GNFk-3_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ATF3 activating transcription factor 3
BIK BCL2-interacting killer (apoptosis-inducing)
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CPVL carboxypeptidase, vitellogenic-like
CTGF connective tissue growth factor
DLC1 DLC1 Rho GTPase activating protein
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DSP desmoplakin
EGFR epidermal growth factor receptor
EMP1 epithelial membrane protein 1
FAS Fas cell surface death receptor
FCGBP Fc fragment of IgG binding protein
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GATA3 GATA binding protein 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HPCAL1 hippocalcin-like 1
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KLF4 Kruppel-like factor 4 (gut)
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LY96 lymphocyte antigen 96
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA1 melanoma antigen family A1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MSLN mesothelin
MSRB2 methionine sulfoxide reductase B2
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
PANX1 pannexin 1
PHYH phytanoyl-CoA 2-hydroxylase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC8 placenta-specific 8
PLAU plasminogen activator, urokinase
PSAP prosaposin
PTX3 pentraxin 3, long
RBKS ribokinase
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN1 sestrin 1
SFN stratifin
SIDT2 SID1 transmembrane family, member 2
SMAD3 SMAD family member 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST18 suppression of tumorigenicity 18, zinc finger
SYNJ2 synaptojanin 2
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM9SF3 transmembrane 9 superfamily member 3
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
WT1 Wilms tumor 1

decreased expression

Symbol Name
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARL4C ADP-ribosylation factor-like 4C
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CA2 carbonic anhydrase II
CBR3 carbonyl reductase 3
CCND2 cyclin D2
CD200 CD200 molecule
CD24 CD24 molecule
CDCA4 cell division cycle associated 4
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFLAR CASP8 and FADD-like apoptosis regulator
EREG epiregulin
FGG fibrinogen gamma chain
FKBP1A FK506 binding protein 1A, 12kDa
FXYD2 FXYD domain containing ion transport regulator 2
GSAP gamma-secretase activating protein
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H1FX H1 histone family, member X
HES1 hes family bHLH transcription factor 1
HGD homogentisate 1,2-dioxygenase
IFITM1 interferon induced transmembrane protein 1
KRT23 keratin 23, type I
LAMB1 laminin, beta 1
LXN latexin
MARCKS myristoylated alanine-rich protein kinase C substrate
MELK maternal embryonic leucine zipper kinase
MYH10 myosin, heavy chain 10, non-muscle
NTS neurotensin
PLAT plasminogen activator, tissue
POSTN periostin, osteoblast specific factor
PPOX protoporphyrinogen oxidase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RBM3 RNA binding motif (RNP1, RRM) protein 3
RECQL RecQ helicase-like
SCEL sciellin
SIRPA signal-regulatory protein alpha
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TESC tescalcin
TMPO thymopoietin
TNFAIP2 tumor necrosis factor, alpha-induced protein 2