BRD-K87932577_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K87932577_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
AGTR1 angiotensin II receptor, type 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CHMP4A charged multivesicular body protein 4A
CLIC4 chloride intracellular channel 4
CLU clusterin
CPB1 carboxypeptidase B1 (tissue)
CRIP1 cysteine-rich protein 1 (intestinal)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYD dihydropyrimidine dehydrogenase
FAS Fas cell surface death receptor
FHL1 four and a half LIM domains 1
FOSL1 FOS-like antigen 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GPER1 G protein-coupled estrogen receptor 1
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
LY75 lymphocyte antigen 75
MAP7 microtubule-associated protein 7
MEF2C myocyte enhancer factor 2C
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PLAC8 placenta-specific 8
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RAP1GAP RAP1 GTPase activating protein
RHOB ras homolog family member B
S100A8 S100 calcium binding protein A8
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SRGN serglycin
TFF1 trefoil factor 1
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TMPRSS3 transmembrane protease, serine 3
TPBG trophoblast glycoprotein
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
ARG1 arginase 1
ASS1 argininosuccinate synthase 1
BCL6 B-cell CLL/lymphoma 6
C14ORF132 chromosome 14 open reading frame 132
C3ORF14 chromosome 3 open reading frame 14
CALML5 calmodulin-like 5
CCL20 chemokine (C-C motif) ligand 20
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
FILIP1L filamin A interacting protein 1-like
FLG filaggrin
HAL histidine ammonia-lyase
IFITM1 interferon induced transmembrane protein 1
IGHM immunoglobulin heavy constant mu
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTB lymphotoxin beta (TNF superfamily, member 3)
MAN1C1 mannosidase, alpha, class 1C, member 1
PARP2 poly (ADP-ribose) polymerase 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB15 RAB15, member RAS oncogene family
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TFRC transferrin receptor
TTC3 tetratricopeptide repeat domain 3
TUBB2A tubulin, beta 2A class IIa