BRD-K87904882_chelerythrine chloride_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K87904882_chelerythrine chloride_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ANXA10 annexin A10
ASS1 argininosuccinate synthase 1
BEX1 brain expressed, X-linked 1
C7 complement component 7
CD52 CD52 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
COL14A1 collagen, type XIV, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CXCL13 chemokine (C-X-C motif) ligand 13
DKK1 dickkopf WNT signaling pathway inhibitor 1
ECM1 extracellular matrix protein 1
EPAS1 endothelial PAS domain protein 1
GNB5 guanine nucleotide binding protein (G protein), beta 5
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LEPR leptin receptor
LIMCH1 LIM and calponin homology domains 1
MELK maternal embryonic leucine zipper kinase
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPY1R neuropeptide Y receptor Y1
PTGES prostaglandin E synthase
RHOBTB3 Rho-related BTB domain containing 3
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC35G2 solute carrier family 35, member G2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
STEAP3 STEAP family member 3, metalloreductase
STX3 syntaxin 3
TNS3 tensin 3
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ADA adenosine deaminase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANPEP alanyl (membrane) aminopeptidase
APOD apolipoprotein D
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA1 carbonic anhydrase I
CCL2 chemokine (C-C motif) ligand 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFLAR CASP8 and FADD-like apoptosis regulator
CKAP4 cytoskeleton-associated protein 4
CKB creatine kinase, brain
CLCA1 chloride channel accessory 1
CLDN3 claudin 3
COL9A3 collagen, type IX, alpha 3
CTSZ cathepsin Z
DEPTOR DEP domain containing MTOR-interacting protein
F2RL1 coagulation factor II (thrombin) receptor-like 1
HBB hemoglobin, beta
HBD hemoglobin, delta
HK2 hexokinase 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IL1R2 interleukin 1 receptor, type II
IQGAP2 IQ motif containing GTPase activating protein 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
MMP7 matrix metallopeptidase 7
NDRG1 N-myc downstream regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NREP neuronal regeneration related protein
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PFKL phosphofructokinase, liver
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAGL1 pleiomorphic adenoma gene-like 1
POSTN periostin, osteoblast specific factor
PROM1 prominin 1
PUF60 poly-U binding splicing factor 60KDa
RPL37A ribosomal protein L37a
SCGB2A1 secretoglobin, family 2A, member 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SPAG4 sperm associated antigen 4
SQLE squalene epoxidase
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VCAN versican
ZG16 zymogen granule protein 16
ZNF274 zinc finger protein 274