BRD-K87737963_CYT387_SKBR3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K87737963_CYT387_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
CES1 carboxylesterase 1
CFD complement factor D (adipsin)
CPE carboxypeptidase E
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
DPYSL3 dihydropyrimidinase-like 3
DRAM1 DNA-damage regulated autophagy modulator 1
DUSP4 dual specificity phosphatase 4
ECHDC3 enoyl CoA hydratase domain containing 3
FGG fibrinogen gamma chain
HYOU1 hypoxia up-regulated 1
IRS2 insulin receptor substrate 2
KCTD14 potassium channel tetramerization domain containing 14
KIAA1033 KIAA1033
LAMP2 lysosomal-associated membrane protein 2
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MME membrane metallo-endopeptidase
MSLN mesothelin
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NXN nucleoredoxin
OBSL1 obscurin-like 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNA proliferating cell nuclear antigen
PGC progastricsin (pepsinogen C)
PPIF peptidylprolyl isomerase F
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
STK26 serine/threonine protein kinase 26
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOLD1 apolipoprotein L domain containing 1
BAMBI BMP and activin membrane-bound inhibitor
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD24 CD24 molecule
CDC20 cell division cycle 20
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP5 dual specificity phosphatase 5
FABP4 fatty acid binding protein 4, adipocyte
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPM6A glycoprotein M6A
HMOX1 heme oxygenase 1
IFI16 interferon, gamma-inducible protein 16
LTF lactotransferrin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLK1 polo-like kinase 1
PODXL podocalyxin-like
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBM34 RNA binding motif protein 34
RGS4 regulator of G-protein signaling 4
THBD thrombomodulin
TMOD1 tropomodulin 1
TSPAN12 tetraspanin 12