BRD-K87737963_CYT387_MCF7_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

111 genes differentially expressed following the BRD-K87737963_CYT387_MCF7_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
APOE apolipoprotein E
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BHLHE41 basic helix-loop-helix family, member e41
BST2 bone marrow stromal cell antigen 2
C6ORF48 chromosome 6 open reading frame 48
CCL20 chemokine (C-C motif) ligand 20
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CHN1 chimerin 1
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CSTA cystatin A (stefin A)
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS9 dehydrogenase/reductase (SDR family) member 9
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
FGFR2 fibroblast growth factor receptor 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXJ3 forkhead box J3
FPR1 formyl peptide receptor 1
GAS1 growth arrest-specific 1
GPATCH8 G patch domain containing 8
IFI6 interferon, alpha-inducible protein 6
IGF1R insulin-like growth factor 1 receptor
KRT17 keratin 17, type I
KYNU kynureninase
LAMB3 laminin, beta 3
LGALS1 lectin, galactoside-binding, soluble, 1
LTF lactotransferrin
MFAP2 microfibrillar-associated protein 2
MGP matrix Gla protein
MMP7 matrix metallopeptidase 7
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MUC16 mucin 16, cell surface associated
MX2 MX dynamin-like GTPase 2
PLAC8 placenta-specific 8
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRRC2C proline-rich coiled-coil 2C
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCYL3 SCY1-like 3 (S. cerevisiae)
SELL selectin L
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SON SON DNA binding protein
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SSBP2 single-stranded DNA binding protein 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMC5 transmembrane channel-like 5
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TUSC3 tumor suppressor candidate 3
WDTC1 WD and tetratricopeptide repeats 1
ZHX2 zinc fingers and homeoboxes 2

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADRB2 adrenoceptor beta 2, surface
ALCAM activated leukocyte cell adhesion molecule
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CA12 carbonic anhydrase XII
CCNF cyclin F
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELF2 CUGBP, Elav-like family member 2
CHL1 cell adhesion molecule L1-like
CLIC3 chloride intracellular channel 3
COBLL1 cordon-bleu WH2 repeat protein-like 1
CST1 cystatin SN
CXCL14 chemokine (C-X-C motif) ligand 14
CYTL1 cytokine-like 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FDXR ferredoxin reductase
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCH1 GTP cyclohydrolase 1
GREB1 growth regulation by estrogen in breast cancer 1
HMGA2 high mobility group AT-hook 2
HMGB2 high mobility group box 2
HN1 hematological and neurological expressed 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
KIAA1033 KIAA1033
LBR lamin B receptor
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LY6D lymphocyte antigen 6 complex, locus D
MAN1A1 mannosidase, alpha, class 1A, member 1
MFAP5 microfibrillar associated protein 5
MYO5C myosin VC
NNMT nicotinamide N-methyltransferase
NRCAM neuronal cell adhesion molecule
NUP85 nucleoporin 85kDa
NUSAP1 nucleolar and spindle associated protein 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RRM2 ribonucleotide reductase M2
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SPP1 secreted phosphoprotein 1
STAR steroidogenic acute regulatory protein
TACC1 transforming, acidic coiled-coil containing protein 1
TAGLN transgelin
TESC tescalcin
TGIF1 TGFB-induced factor homeobox 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNS3 tensin 3
TYMS thymidylate synthetase
ZWINT ZW10 interacting kinetochore protein