BRD-K87737963_CYT387_MCF10A_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K87737963_CYT387_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOE apolipoprotein E
CXCR4 chemokine (C-X-C motif) receptor 4
CYB561 cytochrome b561
DCLK1 doublecortin-like kinase 1
DSP desmoplakin
DUSP6 dual specificity phosphatase 6
DVL1 dishevelled segment polarity protein 1
EFHD1 EF-hand domain family, member D1
EGR1 early growth response 1
FAM129A family with sequence similarity 129, member A
FGFR2 fibroblast growth factor receptor 2
GSN gelsolin
HES1 hes family bHLH transcription factor 1
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
LAPTM4B lysosomal protein transmembrane 4 beta
PAM peptidylglycine alpha-amidating monooxygenase
PFKL phosphofructokinase, liver
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RGS1 regulator of G-protein signaling 1
S100A7 S100 calcium binding protein A7
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SOX9 SRY (sex determining region Y)-box 9
SPG20 spastic paraplegia 20 (Troyer syndrome)

decreased expression

Symbol Name
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
C6ORF62 chromosome 6 open reading frame 62
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCNF cyclin F
CEMIP cell migration inducing protein, hyaluronan binding
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CREB1 cAMP responsive element binding protein 1
CXCL3 chemokine (C-X-C motif) ligand 3
GBP2 guanylate binding protein 2, interferon-inducible
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL6 interleukin 6
LBH limb bud and heart development
MID1 midline 1
OLFM1 olfactomedin 1
PEX11A peroxisomal biogenesis factor 11 alpha
PLK1 polo-like kinase 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RHOBTB3 Rho-related BTB domain containing 3
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SNAP25 synaptosomal-associated protein, 25kDa
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
TARP TCR gamma alternate reading frame protein
TGIF1 TGFB-induced factor homeobox 1
TXNL4B thioredoxin-like 4B
VAV3 vav 3 guanine nucleotide exchange factor
WNT5A wingless-type MMTV integration site family, member 5A
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)