BRD-K87737963_CYT387_HS578T_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

143 genes differentially expressed following the BRD-K87737963_CYT387_HS578T_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANXA4 annexin A4
ASS1 argininosuccinate synthase 1
ATXN1 ataxin 1
B3GNT1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CA12 carbonic anhydrase XII
CCPG1 cell cycle progression 1
CD44 CD44 molecule (Indian blood group)
CLDN10 claudin 10
COL6A1 collagen, type VI, alpha 1
COLEC12 collectin sub-family member 12
CPD carboxypeptidase D
CTSH cathepsin H
CXCL13 chemokine (C-X-C motif) ligand 13
CYB561 cytochrome b561
CYTL1 cytokine-like 1
DALRD3 DALR anticodon binding domain containing 3
DPYD dihydropyrimidine dehydrogenase
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ETFB electron-transfer-flavoprotein, beta polypeptide
FAM65B family with sequence similarity 65, member B
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GPR88 G protein-coupled receptor 88
GPX3 glutathione peroxidase 3
HIST1H2BK histone cluster 1, H2bk
HTRA1 HtrA serine peptidase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IVNS1ABP influenza virus NS1A binding protein
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0125 KIAA0125
LOXL1 lysyl oxidase-like 1
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NMU neuromedin U
NRP1 neuropilin 1
OBSL1 obscurin-like 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PBX1 pre-B-cell leukemia homeobox 1
PDE10A phosphodiesterase 10A
PLAC8 placenta-specific 8
PRKCB protein kinase C, beta
RBKS ribokinase
REEP5 receptor accessory protein 5
RPL31 ribosomal protein L31
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SESN1 sestrin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A18 solute carrier family 22, member 18
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPATA20 spermatogenesis associated 20
SST somatostatin
TMEM45A transmembrane protein 45A
TSC22D3 TSC22 domain family, member 3
TSPAN4 tetraspanin 4
TXNIP thioredoxin interacting protein
VCAN versican

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATAD2 ATPase family, AAA domain containing 2
BHLHE41 basic helix-loop-helix family, member e41
C10ORF10 chromosome 10 open reading frame 10
C3ORF52 chromosome 3 open reading frame 52
CALD1 caldesmon 1
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CCNE2 cyclin E2
CDC42 cell division cycle 42
CDC6 cell division cycle 6
CENPU centromere protein U
CNN1 calponin 1, basic, smooth muscle
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTBP2 C-terminal binding protein 2
CTGF connective tissue growth factor
DHFR dihydrofolate reductase
DMD dystrophin
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP5 dual specificity phosphatase 5
EDN1 endothelin 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FEN1 flap structure-specific endonuclease 1
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
GINS2 GINS complex subunit 2 (Psf2 homolog)
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBB hemoglobin, beta
IER3 immediate early response 3
IGF1 insulin-like growth factor 1 (somatomedin C)
JAG1 jagged 1
KIAA0226L KIAA0226-like
KLF6 Kruppel-like factor 6
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRP4 low density lipoprotein receptor-related protein 4
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MCAM melanoma cell adhesion molecule
MCM10 minichromosome maintenance complex component 10
MMP12 matrix metallopeptidase 12
MUC1 mucin 1, cell surface associated
MYBPC1 myosin binding protein C, slow type
MYH11 myosin, heavy chain 11, smooth muscle
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUP85 nucleoporin 85kDa
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM3 PDZ and LIM domain 3
PDLIM5 PDZ and LIM domain 5
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLA2G16 phospholipase A2, group XVI
RAD51AP1 RAD51 associated protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFC3 replication factor C (activator 1) 3, 38kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SCGB1D2 secretoglobin, family 1D, member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP4 secreted frizzled-related protein 4
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SRGN serglycin
STEAP1 six transmembrane epithelial antigen of the prostate 1
SYNM synemin, intermediate filament protein
TACSTD2 tumor-associated calcium signal transducer 2
TAGLN transgelin
TGFBR3 transforming growth factor, beta receptor III
TMEM255A transmembrane protein 255A
TMPO thymopoietin
TPM2 tropomyosin 2 (beta)
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
UCK2 uridine-cytidine kinase 2
WNT5A wingless-type MMTV integration site family, member 5A