BRD-K87510569_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K87510569_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CD36 CD36 molecule (thrombospondin receptor)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FADS1 fatty acid desaturase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SNX11 sorting nexin 11

decreased expression

Symbol Name
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CXCL10 chemokine (C-X-C motif) ligand 10
DLK1 delta-like 1 homolog (Drosophila)
IDO1 indoleamine 2,3-dioxygenase 1
MMP12 matrix metallopeptidase 12
PDE4B phosphodiesterase 4B, cAMP-specific
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RGS2 regulator of G-protein signaling 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SULF1 sulfatase 1
TRD T cell receptor delta locus
VEGFA vascular endothelial growth factor A